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MGI:Tshr
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Tshr ( synonyms: hypothroid, hyt, pet ) | |
| Protein Name(s) | thyroid stimulating hormone receptor, | |
| External Links | ||
| MGI | MGI:98849 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004871 |
signal transducer activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004930 |
G-protein coupled receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
F |
From MGI |
||
| GO:0004996 |
thyroid-stimulating hormone receptor activity |
MGI:MGI:2137463 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004996 |
thyroid-stimulating hormone receptor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004996 |
thyroid-stimulating hormone receptor activity |
MGI:MGI:74157 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2137463 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:74157 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007189 |
activation of adenylate cyclase activity by G-protein signaling pathway |
MGI:MGI:2137463 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008344 |
adult locomotory behavior |
MGI:MGI:2677535 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856914 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016500 |
protein-hormone receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030183 |
B cell differentiation |
MGI:MGI:3640879 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856914 |
P |
From MGI |
||
| GO:0040012 |
regulation of locomotion |
MGI:MGI:2677535 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856914 |
P |
From MGI |
||
| GO:0040018 |
positive regulation of multicellular organism growth |
MGI:MGI:2677535 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1859614 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Neumann S et al. (2001) Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity. Horm Metab Res 33: 263-9 PubMed GONUTS page
- ↑ 2.0 2.1 Gu WX et al. (1995) The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding. Endocrinology 136: 3146-53 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Kincaid AE (2001) Spontaneous circling behavior and dopamine neuron loss in a genetically hypothyroid mouse. Neuroscience 105: 891-8 PubMed GONUTS page
- ↑ Montecino-Rodriguez E et al. (1997) Primary B cell development is impaired in mice with defects of the pituitary/thyroid axis. J Immunol 159: 2712-9 PubMed GONUTS page
