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MGI:Trf
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Trf ( synonyms: HP, Tfn ) | |
| Protein Name(s) | transferrin, | |
| External Links | ||
| MGI | MGI:98821 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005576 |
extracellular region |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:3056883 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:3609504 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:3790551 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005769 |
early endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005770 |
late endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005905 |
coated pit |
MGI:MGI:4830632 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005905 |
coated pit |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006811 |
ion transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0406 |
P |
From MGI |
||
| GO:0006826 |
iron ion transport |
MGI:MGI:2654570 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856905 |
P |
From MGI |
||
| GO:0006879 |
cellular iron ion homeostasis |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007015 |
actin filament organization |
MGI:MGI:3838421 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007257 |
activation of JUN kinase activity |
MGI:MGI:3838421 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008199 |
ferric iron binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0009925 |
basal plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0015091 |
ferric iron transmembrane transporter activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015682 |
ferric iron transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016023 |
cytoplasmic membrane-bounded vesicle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030139 |
endocytic vesicle |
MGI:MGI:2446998 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030139 |
endocytic vesicle |
MGI:MGI:3051925 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030139 |
endocytic vesicle |
MGI:MGI:3513645 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030316 |
osteoclast differentiation |
MGI:MGI:3838421 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0031643 |
positive regulation of myelination |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034755 |
iron ion transmembrane transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042327 |
positive regulation of phosphorylation |
MGI:MGI:3838421 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045178 |
basal part of cell |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045780 |
positive regulation of bone resorption |
MGI:MGI:3838421 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3838421 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0055037 |
recycling endosome |
MGI:MGI:3691553 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0055037 |
recycling endosome |
MGI:MGI:3822406 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0055037 |
recycling endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0055072 |
iron ion homeostasis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0410 |
P |
From MGI |
||
| GO:0060395 |
SMAD protein signal transduction |
MGI:MGI:1195384 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070371 |
ERK1 and ERK2 cascade |
MGI:MGI:3838421 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0072512 |
trivalent inorganic cation transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2000147 |
positive regulation of cell motility |
MGI:MGI:3838421 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Guilherme A et al. (2004) Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes. J Biol Chem 279: 40062-75 PubMed GONUTS page
- ↑ Ohgami RS et al. (2005) Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat Genet 37: 1264-9 PubMed GONUTS page
- ↑ Capurro MI et al. (2008) Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding. Dev Cell 14: 700-11 PubMed GONUTS page
- ↑ Molla-Herman A et al. (2010) The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia. J Cell Sci 123: 1785-95 PubMed GONUTS page
- ↑ McKie AT et al. (2001) An iron-regulated ferric reductase associated with the absorption of dietary iron. Science 291: 1755-9 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 Ishii KA et al. (2009) Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation. Nat Med 15: 259-66 PubMed GONUTS page
- ↑ Galperin E et al. (2002) EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1. Traffic 3: 575-89 PubMed GONUTS page
- ↑ Simonsen A et al. (2004) Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J Cell Sci 117: 4239-51 PubMed GONUTS page
- ↑ Coumailleau F et al. (2004) Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment. Mol Biol Cell 15: 4444-56 PubMed GONUTS page
- ↑ Canonne-Hergaux F et al. (2001) Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice. Blood 98: 3823-30 PubMed GONUTS page
- ↑ Uechi Y et al. (2009) Rap2 function requires palmitoylation and recycling endosome localization. Biochem Biophys Res Commun 378: 732-7 PubMed GONUTS page
- ↑ Sirard C et al. (1998) The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. Genes Dev 12: 107-19 PubMed GONUTS page
