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MGI:Top1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Top1 ( synonyms: Top-1 ) | |
| Protein Name(s) | topoisomerase (DNA) I, | |
| External Links | ||
| MGI | MGI:98788 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000932 |
cytoplasmic mRNA processing body |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_072137 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003916 |
DNA topoisomerase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0799 |
F |
From MGI |
||
| GO:0003917 |
DNA topoisomerase type I activity |
MGI:MGI:3612364 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003917 |
DNA topoisomerase type I activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_072137 |
F |
From MGI |
||
| GO:0003917 |
DNA topoisomerase type I activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003917 |
DNA topoisomerase type I activity |
MGI:MGI:70738 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003917 |
DNA topoisomerase type I activity |
MGI:MGI:86770 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003918 |
DNA topoisomerase (ATP-hydrolyzing) activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3612364 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_072137 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:83974 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:86770 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005654 |
nucleoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005694 |
chromosome |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001631 |
C |
From MGI |
||
| GO:0005730 |
nucleolus |
MGI:MGI:4459044 |
PANTHER:PTHR10290 |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3612364 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006260 |
DNA replication |
MGI:MGI:2157189 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006265 |
DNA topological change |
MGI:MGI:3612364 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006265 |
DNA topological change |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_072137 |
P |
From MGI |
||
| GO:0006265 |
DNA topological change |
MGI:MGI:70738 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009303 |
rRNA transcription |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_072137 |
P |
From MGI |
||
| GO:0016853 |
isomerase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0413 |
F |
From MGI |
||
| GO:0031490 |
chromatin DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_072137 |
F |
From MGI |
||
| GO:0031490 |
chromatin DNA binding |
MGI:MGI:4459044 |
PANTHER:PTHR10290 |
F |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_072137 |
F |
From MGI |
||
| GO:0040016 |
embryonic cleavage |
MGI:MGI:83974 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2678314 |
P |
From MGI |
||
| GO:0043204 |
perikaryon |
MGI:MGI:3612364 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Plaschkes I et al. (2005) DNA topoisomerase I in the mouse central nervous system: Age and sex dependence. J Comp Neurol 493: 357-69 PubMed GONUTS page
- ↑ 2.0 2.1 Baloch Z et al. (1995) Modulation of topoisomerase activities by tumor necrosis factor. Cell Immunol 160: 98-103 PubMed GONUTS page
- ↑ 3.0 3.1 Cobb J et al. (1997) Analysis of expression and function of topoisomerase I and II during meiosis in male mice. Mol Reprod Dev 46: 489-98 PubMed GONUTS page
- ↑ 4.0 4.1 Morham SG et al. (1996) Targeted disruption of the mouse topoisomerase I gene by camptothecin selection. Mol Cell Biol 16: 6804-9 PubMed GONUTS page
- ↑ Lebel M (2002) Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue. Carcinogenesis 23: 213-6 PubMed GONUTS page
