GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Tnxb
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Tnxb ( synonyms: TN-MHC, Tnx ) | |
| Protein Name(s) | tenascin XB, | |
| External Links | ||
| MGI | MGI:1932137 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005518 |
collagen binding |
MGI:MGI:3052884 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:82758 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:70320 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:70320 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:3531373 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
||
| GO:0006631 |
fatty acid metabolic process |
MGI:MGI:3531373 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
||
| GO:0006641 |
triglyceride metabolic process |
MGI:MGI:3531373 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
||
| GO:0007160 |
cell-matrix adhesion |
MGI:MGI:3607885 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
||
| GO:0008201 |
heparin binding |
MGI:MGI:70320 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0016337 |
cell-cell adhesion |
MGI:MGI:3607885 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
||
| GO:0030198 |
extracellular matrix organization |
MGI:MGI:3052884 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
||
| GO:0030199 |
collagen fibril organization |
MGI:MGI:2177884 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181283 |
P |
From MGI |
||
| GO:0032963 |
collagen metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043206 |
fibril organization |
MGI:MGI:3052887 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
||
| GO:0043506 |
regulation of JUN kinase activity |
MGI:MGI:3691773 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
||
| GO:0048251 |
elastic fiber assembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
NOT |
GO:0006644 |
phospholipid metabolic process |
MGI:MGI:3606822 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053791 |
P |
From MGI |
|
|
NOT |
GO:0045785 |
positive regulation of cell adhesion |
MGI:MGI:70343 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Minamitani T et al. (2004) Modulation of collagen fibrillogenesis by tenascin-X and type VI collagen. Exp Cell Res 298: 305-15 PubMed GONUTS page
- ↑ Sakai T et al. (1996) Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts. J Cell Sci 109 ( Pt 8): 2069-77 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Matsumoto K et al. (1994) The distribution of tenascin-X is distinct and often reciprocal to that of tenascin-C. J Cell Biol 125: 483-93 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Matsumoto K et al. (2004) Triglyceride accumulation and altered composition of triglyceride-associated fatty acids in the skin of tenascin-X-deficient mice. Genes Cells 9: 737-48 PubMed GONUTS page
- ↑ 5.0 5.1 Minamitani T et al. (2002) Adhesive defect in extracellular matrix tenascin-X-null fibroblasts: a possible mechanism of tumor invasion. Biol Pharm Bull 25: 1472-5 PubMed GONUTS page
- ↑ Mao JR et al. (2002) Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition. Nat Genet 30: 421-5 PubMed GONUTS page
- ↑ Minamitani T et al. (2004) Deficiency of tenascin-X causes a decrease in the level of expression of type VI collagen. Exp Cell Res 297: 49-60 PubMed GONUTS page
- ↑ Matsumoto K et al. (2004) Induction of matrix metalloproteinase-2 by tenascin-X deficiency is mediated through the c-Jun N-terminal kinase and protein tyrosine kinase phosphorylation pathway. Exp Cell Res 297: 404-14 PubMed GONUTS page
- ↑ Matsumoto K et al. (2004) Comparison of the compositions of phospholipid-associated fatty acids in wild-type and extracellular matrix tenascin-X-deficient mice. Biol Pharm Bull 27: 1447-50 PubMed GONUTS page
- ↑ Yoshikawa K et al. (1995) Molecular cloning of the gene coding for the mouse T-cell antigen CD7. Immunogenetics 41: 159-61 PubMed GONUTS page
