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MGI:Tnfrsf12a
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Tnfrsf12a ( synonyms: Fn14, TWEAK-R, TweakR ) | |
| Protein Name(s) | tumor necrosis factor receptor superfamily, member 12a, | |
| External Links | ||
| MGI | MGI:1351484 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001525 |
angiogenesis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0037 |
P |
From MGI |
||
| GO:0001726 |
ruffle |
MGI:MGI:2679391 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:2679391 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1347374 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0053 |
P |
From MGI |
||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006931 |
substrate-dependent cell migration, cell attachment to substrate |
MGI:MGI:1347374 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:1347374 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0008219 |
cell death |
MGI:MGI:2667292 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:2667292 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0045773 |
positive regulation of axon extension |
MGI:MGI:2679391 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:2001238 |
positive regulation of extrinsic apoptotic signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Tanabe K et al. (2003) Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth. J Neurosci 23: 9675-86 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Meighan-Mantha RL et al. (1999) The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J Biol Chem 274: 33166-76 PubMed GONUTS page
- ↑ 3.0 3.1 Nakayama M et al. (2003) Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies. Biochem Biophys Res Commun 306: 819-25 PubMed GONUTS page
