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MGI:Tlx3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Tlx3 ( synonyms: Hox11l2, Rnx, Tlx1l2 ) | |
| Protein Name(s) | T cell leukemia, homeobox 3, | |
| External Links | ||
| MGI | MGI:1351209 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001708 |
cell fate specification |
MGI:MGI:3044254 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98769 |
P |
From MGI |
||
| GO:0001708 |
cell fate specification |
MGI:MGI:3044254 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180105 |
P |
From MGI |
||
| GO:0001764 |
neuron migration |
MGI:MGI:3051709 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180105 |
P |
From MGI |
||
| GO:0002087 |
regulation of respiratory gaseous exchange by neurological system process |
MGI:MGI:3626029 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180105 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3505657 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3505657 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007417 |
central nervous system development |
MGI:MGI:2179900 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857260 |
P |
From MGI |
||
| GO:0007585 |
respiratory gaseous exchange |
MGI:MGI:1353862 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857260 |
P |
From MGI |
||
| GO:0030182 |
neuron differentiation |
MGI:MGI:2179900 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857260 |
P |
From MGI |
||
| GO:0045665 |
negative regulation of neuron differentiation |
MGI:MGI:3607682 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104867 |
P |
From MGI |
||
| GO:0048665 |
neuron fate specification |
MGI:MGI:3607682 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104867 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Cheng L et al. (2004) Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci 7: 510-7 PubMed GONUTS page
- ↑ Ding YQ et al. (2004) Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord. Development 131: 3693-703 PubMed GONUTS page
- ↑ Onimaru H et al. (2004) In vitro visualization of respiratory neuron activity in the newborn mouse ventral medulla. Brain Res Dev Brain Res 153: 275-9 PubMed GONUTS page
- ↑ 4.0 4.1 Rhee JW et al. (2004) Pbx3 deficiency results in central hypoventilation. Am J Pathol 165: 1343-50 PubMed GONUTS page
- ↑ 5.0 5.1 Qian Y et al. (2002) Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1. Genes Dev 16: 1220-33 PubMed GONUTS page
- ↑ Shirasawa S et al. (2000) Rnx deficiency results in congenital central hypoventilation. Nat Genet 24: 287-90 PubMed GONUTS page
- ↑ 7.0 7.1 Cheng L et al. (2005) Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes. Nat Neurosci 8: 1510-5 PubMed GONUTS page
