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MGI:Tiam2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Tiam2 ( synonyms: STEF )
Protein Name(s) T cell lymphoma invasion and metastasis 2,
External Links
MGI MGI:1344338

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005057

receptor signaling protein activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003116

F

From MGI

GO:0005085

guanyl-nucleotide exchange factor activity

MGI:MGI:1339110
PMID:10364228[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005089

Rho guanyl-nucleotide exchange factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

F

From MGI

GO:0005096

GTPase activator activity

MGI:MGI:2157241
PMID:11707441[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:1339110
PMID:10364228[1]

IPI: Inferred from Physical Interaction

UniProtKB:P15154

F

From MGI

GO:0005543

phospholipid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

C

From MGI

GO:0005624

membrane fraction

MGI:MGI:2157241
PMID:11707441[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2157241
PMID:11707441[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007165

signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003116

P

From MGI

GO:0035023

regulation of Rho protein signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

P

From MGI

GO:0035556

intracellular signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001331

P

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0043547

positive regulation of GTPase activity

MGI:MGI:2157241
PMID:11707441[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:1339110
PMID:10364228[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Hoshino M et al. (1999) Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1. J Biol Chem 274: 17837-44 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Matsuo N et al. (2002) Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth. J Biol Chem 277: 2860-8 PubMed GONUTS page
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