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MGI:Thy1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Thy1 ( synonyms: CD90, T25, Thy 1.2, Thy-1, Thy-1.2, Thy1.1, Thy1.2 ) | |
| Protein Name(s) | thymus cell antigen 1, theta, | |
| External Links | ||
| MGI | MGI:98747 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001525 |
angiogenesis |
MGI:MGI:3687715 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0005100 |
Rho GTPase activator activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005178 |
integrin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006469 |
negative regulation of protein kinase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007010 |
cytoskeleton organization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:3813999 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:67656 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016337 |
cell-cell adhesion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0019901 |
protein kinase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030336 |
negative regulation of cell migration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030425 |
dendrite |
MGI:MGI:3574008 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030426 |
growth cone |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031225 |
anchored to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0336 |
C |
From MGI |
||
| GO:0031362 |
anchored to external side of plasma membrane |
MGI:MGI:1349255 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031362 |
anchored to external side of plasma membrane |
MGI:MGI:2686748 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0032321 |
positive regulation of Rho GTPase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034235 |
GPI anchor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043547 |
positive regulation of GTPase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045121 |
membrane raft |
MGI:MGI:3711602 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0046549 |
retinal cone cell development |
MGI:MGI:1349255 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046658 |
anchored to plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0048041 |
focal adhesion assembly |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050771 |
negative regulation of axonogenesis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050852 |
T cell receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050860 |
negative regulation of T cell receptor signaling pathway |
MGI:MGI:1096761 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050870 |
positive regulation of T cell activation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051281 |
positive regulation of release of sequestered calcium ion into cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lee WS et al. (1998) Thy-1, a novel marker for angiogenesis upregulated by inflammatory cytokines. Circ Res 82: 845-51 PubMed GONUTS page
- ↑ Kim PJ et al. (2006) GATA-3 regulates the development and function of invariant NKT cells. J Immunol 177: 6650-9 PubMed GONUTS page
- ↑ Tiveron MC et al. (1994) The mode of anchorage to the cell surface determines both the function and the membrane location of Thy-1 glycoprotein. J Cell Sci 107 ( Pt 7): 1783-96 PubMed GONUTS page
- ↑ Yoshihara S et al. (2005) Arx homeobox gene is essential for development of mouse olfactory system. Development 132: 751-62 PubMed GONUTS page
- ↑ 5.0 5.1 Simon PD et al. (1999) Thy-1 is critical for normal retinal development. Brain Res Dev Brain Res 117: 219-23 PubMed GONUTS page
- ↑ Jung KC et al. (2004) TCR-independent and caspase-independent apoptosis of murine thymocytes by CD24 cross-linking. J Immunol 172: 795-802 PubMed GONUTS page
- ↑ Hatano T et al. (2007) Leucine-rich repeat kinase 2 associates with lipid rafts. Hum Mol Genet 16: 678-90 PubMed GONUTS page
- ↑ Hueber AO et al. (1997) Thymocytes in Thy-1-/- mice show augmented TCR signaling and impaired differentiation. Curr Biol 7: 705-8 PubMed GONUTS page
