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MGI:Tgif1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Tgif1 ( synonyms: Tgif )
Protein Name(s) TGFB-induced factor homeobox 1,
External Links
MGI MGI:1194497

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

EMBL:AF179900

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3615867
PMID:16428452[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:98214

P

From MGI

GO:0001843

neural tube closure

MGI:MGI:3697552
PMID:17082251[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698004

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008422
InterPro:IPR009057

F

From MGI

GO:0003682

chromatin binding

MGI:MGI:3615867
PMID:16428452[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0005515

protein binding

MGI:MGI:3615867
PMID:16428452[1]

IPI: Inferred from Physical Interaction

UniProtKB:P28700

F

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001015020

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008422
InterPro:IPR001356

P

From MGI

GO:0007368

determination of left/right symmetry

MGI:MGI:3629366
PMID:16705179[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3652354

P

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:3697552
PMID:17082251[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698004

P

From MGI

GO:0008432

JUN kinase binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

EMBL:AF179900

F

From MGI

GO:0009953

dorsal/ventral pattern formation

MGI:MGI:3697552
PMID:17082251[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698004

P

From MGI

GO:0010629

negative regulation of gene expression

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001015020

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0045666

positive regulation of neuron differentiation

MGI:MGI:3826282
PMID:18973577[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0048146

positive regulation of fibroblast proliferation

MGI:MGI:3629366
PMID:16705179[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3652354

P

From MGI

GO:0048387

negative regulation of retinoic acid receptor signaling pathway

MGI:MGI:3615867
PMID:16428452[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3617788

P

From MGI

GO:0060041

retina development in camera-type eye

MGI:MGI:3826282
PMID:18973577[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0070410

co-SMAD binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001015020

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Bartholin L et al. (2006) TGIF inhibits retinoid signaling. Mol Cell Biol 26: 990-1001 PubMed GONUTS page
  2. 2.0 2.1 2.2 Kuang C et al. (2006) Intragenic deletion of Tgif causes defectsin brain development. Hum Mol Genet 15: 3508-19 PubMed GONUTS page
  3. 3.0 3.1 Mar L & Hoodless PA (2006) Embryonic fibroblasts from mice lacking Tgif were defective in cell cycling. Mol Cell Biol 26: 4302-10 PubMed GONUTS page
  4. 4.0 4.1 Zaman V et al. (2008) The nigrostriatal dopamine system of aging GFRalpha-1 heterozygous mice: neurochemistry, morphology and behavior. Eur J Neurosci 28: 1557-68 PubMed GONUTS page
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