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MGI:Tgfb1i1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Tgfb1i1 ( synonyms: ARA55, hic-5, TSC-5 )
Protein Name(s) transforming growth factor beta 1 induced transcript 1,
External Links
MGI MGI:102784

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003713

transcription coactivator activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

F

From MGI

GO:0005515

protein binding

MGI:MGI:3828419
PMID:9756887[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q05397

F

From MGI

GO:0005622

intracellular

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

C

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0005925

focal adhesion

MGI:MGI:2157255
PMID:11784865[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001781

F

From MGI

GO:0009408

response to heat

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001178769

P

From MGI

GO:0010718

positive regulation of epithelial to mesenchymal transition

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

From MGI

GO:0016331

morphogenesis of embryonic epithelium

MGI:MGI:3527921
PMID:15687259[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030054

cell junction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030511

positive regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

P

From MGI

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

P

From MGI

GO:0030579

ubiquitin-dependent SMAD protein catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

P

From MGI

GO:0030855

epithelial cell differentiation

MGI:MGI:3527921
PMID:15687259[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97747

P

From MGI

GO:0045165

cell fate commitment

MGI:MGI:3527921
PMID:15687259[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97747

P

From MGI

GO:0045599

negative regulation of fat cell differentiation

MGI:MGI:3527921
PMID:15687259[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97747

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048495

Roundabout binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

F

From MGI

GO:0050681

androgen receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

F

From MGI

GO:0070411

I-SMAD binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001178769

F

From MGI

GO:0070411

I-SMAD binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43294

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Fujita H et al. (1998) Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase. J Biol Chem 273: 26516-21 PubMed GONUTS page
  2. Hagel M et al. (2002) The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling. Mol Cell Biol 22: 901-15 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Drori S et al. (2005) Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev 19: 362-75 PubMed GONUTS page
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