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MGI:Tet2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Tet2 ( synonyms: Ayu17-449 )
Protein Name(s) tet methylcytosine dioxygenase 2,
External Links
MGI MGI:2443298

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001822

kidney development

MGI:MGI:3813193
PMID:18288583[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3813933

P

From MGI

GO:0005575

cellular component

MGI:MGI:2156816

ND: No biological Data available

C

From MGI

GO:0007049

cell cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From MGI

GO:0009791

post-embryonic development

MGI:MGI:3813193
PMID:18288583[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3813933

P

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0016702

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0223

F

From MGI

GO:0030099

myeloid cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6N021

P

From MGI

GO:0030099

myeloid cell differentiation

MGI:MGI:4888067
PMID:21057493[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0070579

methylcytosine dioxygenase activity

MGI:MGI:3844762
PMID:19372391[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0070579

methylcytosine dioxygenase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6N021

F

From MGI

GO:0070579

methylcytosine dioxygenase activity

MGI:MGI:4888067
PMID:21057493[2]

IMP: Inferred from Mutant Phenotype

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Tang H et al. (2008) Characterization of Ayu17-449 gene expression and resultant kidney pathology in a knockout mouse model. Transgenic Res 17: 599-608 PubMed GONUTS page
  2. 2.0 2.1 Ko M et al. (2010) Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468: 839-43 PubMed GONUTS page
  3. Tahiliani M et al. (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324: 930-5 PubMed GONUTS page
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