![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Tet2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Tet2 ( synonyms: Ayu17-449 ) | |
| Protein Name(s) | tet methylcytosine dioxygenase 2, | |
| External Links | ||
| MGI | MGI:2443298 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001822 |
kidney development |
MGI:MGI:3813193 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3813933 |
P |
From MGI |
||
| GO:0005575 |
cellular component |
MGI:MGI:2156816 |
ND: No biological Data available |
C |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0009791 |
post-embryonic development |
MGI:MGI:3813193 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3813933 |
P |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0223 |
F |
From MGI |
||
| GO:0030099 |
myeloid cell differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030099 |
myeloid cell differentiation |
MGI:MGI:4888067 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0070579 |
methylcytosine dioxygenase activity |
MGI:MGI:3844762 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0070579 |
methylcytosine dioxygenase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0070579 |
methylcytosine dioxygenase activity |
MGI:MGI:4888067 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Tang H et al. (2008) Characterization of Ayu17-449 gene expression and resultant kidney pathology in a knockout mouse model. Transgenic Res 17: 599-608 PubMed GONUTS page
- ↑ 2.0 2.1 Ko M et al. (2010) Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468: 839-43 PubMed GONUTS page
- ↑ Tahiliani M et al. (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324: 930-5 PubMed GONUTS page