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MGI:Terf2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Terf2 ( synonyms: TRF2 ) | |
| Protein Name(s) | telomeric repeat binding factor 2, | |
| External Links | ||
| MGI | MGI:1195972 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000723 |
telomere maintenance |
MGI:MGI:3034120 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0000723 |
telomere maintenance |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000781 |
chromosome, telomeric region |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0000783 |
nuclear telomere cap complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0000784 |
nuclear chromosome, telomeric region |
MGI:MGI:3615734 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000784 |
nuclear chromosome, telomeric region |
MGI:MGI:3719060 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001673 |
male germ cell nucleus |
MGI:MGI:3719060 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001701 |
in utero embryonic development |
MGI:MGI:3615734 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3619525 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003691 |
double-stranded telomeric DNA binding |
MGI:MGI:1097302 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4440768 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4821187 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4830207 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005694 |
chromosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0158 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0008022 |
protein C-terminus binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0010834 |
telomere maintenance via telomere shortening |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016233 |
telomere capping |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031627 |
telomeric loop formation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031848 |
protection from non-homologous end joining at telomere |
MGI:MGI:3615734 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0031848 |
protection from non-homologous end joining at telomere |
MGI:MGI:3615734 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3619525 |
P |
From MGI |
||
| GO:0031848 |
protection from non-homologous end joining at telomere |
MGI:MGI:4830207 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0031848 |
protection from non-homologous end joining at telomere |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032205 |
negative regulation of telomere maintenance |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032206 |
positive regulation of telomere maintenance |
MGI:MGI:3615734 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032206 |
positive regulation of telomere maintenance |
MGI:MGI:3615734 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3619525 |
P |
From MGI |
||
| GO:0042162 |
telomeric DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:1097302 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0070198 |
protein localization to chromosome, telomeric region |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Bailey SM et al. (2004) Dysfunctional mammalian telomeres join with DNA double-strand breaks. DNA Repair (Amst) 3: 349-57 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Celli GB & de Lange T (2005) DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion. Nat Cell Biol 7: 712-8 PubMed GONUTS page
- ↑ 3.0 3.1 Li XC & Schimenti JC (2007) Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. PLoS Genet 3: e130 PubMed GONUTS page
- ↑ 4.0 4.1 Broccoli D et al. (1997) Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nat Genet 17: 231-5 PubMed GONUTS page
- ↑ Sfeir A et al. (2010) Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal. Science 327: 1657-61 PubMed GONUTS page
- ↑ Teo H et al. (2010) Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression. Nat Cell Biol 12: 758-67 PubMed GONUTS page
- ↑ 7.0 7.1 Wu P et al. (2010) Apollo contributes to G overhang maintenance and protects leading-end telomeres. Mol Cell 39: 606-17 PubMed GONUTS page
