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MGI:Terc
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Terc ( synonyms: mTER, mTR ) | |
| Protein Name(s) | telomerase RNA component, | |
| External Links | ||
| MGI | MGI:109558 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000332 |
template for synthesis of G-rich strand of telomere DNA activity |
MGI:MGI:1098058 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
F |
From MGI |
||
| GO:0000723 |
telomere maintenance |
MGI:MGI:3050262 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:109635 |
P |
From MGI |
||
| GO:0000723 |
telomere maintenance |
MGI:MGI:3055614 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:109635 |
P |
From MGI |
||
| GO:0000723 |
telomere maintenance |
MGI:MGI:3700621 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
P |
From MGI |
||
| GO:0003720 |
telomerase activity |
MGI:MGI:3774867 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
F |
From MGI |
||
| GO:0005697 |
telomerase holoenzyme complex |
MGI:MGI:1098058 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
C |
From MGI |
||
| GO:0007004 |
telomere maintenance via telomerase |
MGI:MGI:1098058 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
P |
From MGI |
||
| GO:0008283 |
cell proliferation |
MGI:MGI:3715429 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
P |
From MGI |
||
| GO:0009791 |
post-embryonic development |
MGI:MGI:3715429 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
P |
From MGI |
||
| GO:0010259 |
multicellular organismal aging |
MGI:MGI:3050262 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:109635 |
P |
From MGI |
||
| GO:0032212 |
positive regulation of telomere maintenance via telomerase |
MGI:MGI:3774867 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
P |
From MGI |
||
| GO:0042127 |
regulation of cell proliferation |
MGI:MGI:2135372 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88039 |
P |
From MGI |
||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:3715429 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
P |
From MGI |
||
| GO:0060218 |
hemopoietic stem cell differentiation |
MGI:MGI:3715429 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857930 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Elenius K et al. (1997) A novel juxtamembrane domain isoform of HER4/ErbB4. Isoform-specific tissue distribution and differential processing in response to phorbol ester. J Biol Chem 272: 26761-8 PubMed GONUTS page
- ↑ 2.0 2.1 Chang S et al. (2004) Essential role of limiting telomeres in the pathogenesis of Werner syndrome. Nat Genet 36: 877-82 PubMed GONUTS page
- ↑ Du X et al. (2004) Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes. Mol Cell Biol 24: 8437-46 PubMed GONUTS page
- ↑ Maser RS et al. (2007) DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse. Mol Cell Biol 27: 2253-65 PubMed GONUTS page
- ↑ 5.0 5.1 Liu L et al. (2007) Telomere lengthening early in development. Nat Cell Biol 9: 1436-41 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Rossi DJ et al. (2007) Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 447: 725-9 PubMed GONUTS page
- ↑ Rudolph KL et al. (2001) Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat Genet 28: 155-9 PubMed GONUTS page
