Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Tcrb

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Tcrb ( synonyms: TCRbeta, Tib )
Protein Name(s) T-cell receptor beta chain,
External Links
MGI MGI:98578

Annotations

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0009897

external side of plasma membrane

MGI:MGI:1354083
PMID:10704459[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3054293
PMID:15294943[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3686949
PMID:16973387[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3700459
PMID:16301745[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:78866
PMID:8788039[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:893249
PMID:9208839[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042105

alpha-beta T cell receptor complex

MGI:MGI:82729
PMID:9064344[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042105

alpha-beta T cell receptor complex

MGI:MGI:893249
PMID:9208839[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042277

peptide binding

MGI:MGI:3769991
PMID:8612131[8]

IPI: Inferred from Physical Interaction

F

From MGI

GO:0045778

positive regulation of ossification

MGI:MGI:4358631
PMID:19723499[9]

IGI: Inferred from Genetic Interaction

MGI:MGI:108061

P

From MGI

GO:0045778

positive regulation of ossification

MGI:MGI:4358631
PMID:19723499[9]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857256

P

From MGI

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

MGI:MGI:893249
PMID:9208839[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050850

positive regulation of calcium-mediated signaling

MGI:MGI:893249
PMID:9208839[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050852

T cell receptor signaling pathway

MGI:MGI:893249
PMID:9208839[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050870

positive regulation of T cell activation

MGI:MGI:72888
PMID:7538697[10]

IDA: Inferred from Direct Assay

P

From MGI

GO:0071374

cellular response to parathyroid hormone stimulus

MGI:MGI:4358631
PMID:19723499[9]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857256

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Kennedy MK et al. (2000) Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 191: 771-80 PubMed GONUTS page
  2. Kang J et al. (2004) STAT5 is required for thymopoiesis in a development stage-specific manner. J Immunol 173: 2307-14 PubMed GONUTS page
  3. Marie JC et al. (2006) Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity 25: 441-54 PubMed GONUTS page
  4. Chen Z et al. (2005) Where CD4+CD25+ T reg cells impinge on autoimmune diabetes. J Exp Med 202: 1387-97 PubMed GONUTS page
  5. Li T et al. (1996) Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes. Cell Growth Differ 7: 107-14 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Wiest DL et al. (1997) A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development. Immunity 6: 663-71 PubMed GONUTS page
  7. Pani G et al. (1996) Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase. J Exp Med 184: 839-52 PubMed GONUTS page
  8. Sant'Angelo DB et al. (1996) The specificity and orientation of a TCR to its peptide-MHC class II ligands. Immunity 4: 367-76 PubMed GONUTS page
  9. 9.0 9.1 9.2 Terauchi M et al. (2009) T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell Metab 10: 229-40 PubMed GONUTS page
  10. Bendelac A et al. (1995) CD1 recognition by mouse NK1+ T lymphocytes. Science 268: 863-5 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox