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MGI:Tcfeb

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Tcfeb ( synonyms: bHLHe35, TFEB )
Protein Name(s) transcription factor EB,
External Links
MGI MGI:103270

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001892

embryonic placenta development

MGI:MGI:1306865
PMID:9806910[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0003677

DNA binding

MGI:MGI:3590422
PMID:15994295[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:3662947
PMID:16936731[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19484

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19484

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:3590422
PMID:15994295[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19484

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19484

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR024097,InterPro:IPR021802

P

From MGI

GO:0006959

humoral immune response

MGI:MGI:3662947
PMID:16936731[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0044212

transcription regulatory region DNA binding

MGI:MGI:3662947
PMID:16936731[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0044212

transcription regulatory region DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19484

F

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:3590422
PMID:15994295[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3662947
PMID:16936731[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19484

P

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:3662947
PMID:16936731[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q64092

F

From MGI

GO:0046983

protein dimerization activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR024098

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Steingrímsson E et al. (1998) The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. Development 125: 4607-16 PubMed GONUTS page
  2. 2.0 2.1 2.2 Huan C et al. (2005) Renal carcinoma-associated transcription factors TFE3 and TFEB are leukemia inhibitory factor-responsive transcription activators of E-cadherin. J Biol Chem 280: 30225-35 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Huan C et al. (2006) Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity. Nat Immunol 7: 1082-91 PubMed GONUTS page
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