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MGI:Tbp
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Tbp ( synonyms: Gtf2d ) | |
| Protein Name(s) | TATA box binding protein, | |
| External Links | ||
| MGI | MGI:101838 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000120 |
RNA polymerase I transcription factor complex |
MGI:MGI:86398 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0001103 |
RNA polymerase II repressing transcription factor binding |
MGI:MGI:3837061 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0001939 |
female pronucleus |
MGI:MGI:3717961 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001940 |
male pronucleus |
MGI:MGI:3717961 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3525928 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3790882 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3806427 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001004198 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:1202493 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3663197 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q8BMU0 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:5009206 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2159505 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2429335 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2450488 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2661255 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3583836 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3663197 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3709925 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3717961 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3806427 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001004198 |
C |
From MGI |
||
| GO:0005669 |
transcription factor TFIID complex |
MGI:MGI:2679136 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005669 |
transcription factor TFIID complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001004198 |
C |
From MGI |
||
| GO:0005669 |
transcription factor TFIID complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005672 |
transcription factor TFIIA complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005719 |
nuclear euchromatin |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2661255 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006366 |
transcription from RNA polymerase II promoter |
MGI:MGI:2429335 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429772 |
P |
From MGI |
||
| GO:0006366 |
transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006367 |
transcription initiation from RNA polymerase II promoter |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006383 |
transcription from RNA polymerase III promoter |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006383 |
transcription from RNA polymerase III promoter |
MGI:MGI:2429335 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429772 |
P |
From MGI |
||
| GO:0008134 |
transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045120 |
pronucleus |
MGI:MGI:3664825 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001004198 |
P |
From MGI |
||
| GO:0070491 |
repressing transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
|
contributes_to |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001004198 |
F |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Heix J et al. (1997) Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1. Proc Natl Acad Sci U S A 94: 1733-8 PubMed GONUTS page
- ↑ Anderson DM et al. (2009) The homeobox gene Mohawk represses transcription by recruiting the sin3A/HDAC co-repressor complex. Dev Dyn 238: 572-80 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gazdag E et al. (2007) Analysis of TATA-binding protein 2 (TBP2) and TBP expression suggests different roles for the two proteins in regulation of gene expression during oogenesis and early mouse development. Reproduction 134: 51-62 PubMed GONUTS page
- ↑ Kabe Y et al. (2005) NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes. Mol Cell Biol 25: 512-22 PubMed GONUTS page
- ↑ Friedman MJ et al. (2008) Polyglutamine expansion reduces the association of TATA-binding protein with DNA and induces DNA binding-independent neurotoxicity. J Biol Chem 283: 8283-90 PubMed GONUTS page
- ↑ 6.0 6.1 Tatarakis A et al. (2008) Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. Mol Cell 31: 531-43 PubMed GONUTS page
- ↑ Okuda A et al. (1998) UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells. EMBO J 17: 2019-32 PubMed GONUTS page
- ↑ 8.0 8.1 Prigge JR & Schmidt EE (2006) Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP. J Biol Chem 281: 12260-9 PubMed GONUTS page
- ↑ Glenn DJ & Maurer RA (1999) MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression. J Biol Chem 274: 36159-67 PubMed GONUTS page
- ↑ Martianov I et al. (2002) Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids. Development 129: 945-55 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Martianov I et al. (2002) RNA polymerase II transcription in murine cells lacking the TATA binding protein. Science 298: 1036-9 PubMed GONUTS page
- ↑ Schmidt EE et al. (2003) Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein. J Biol Chem 278: 6168-74 PubMed GONUTS page
- ↑ 13.0 13.1 Pointud JC et al. (2003) The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation. J Cell Sci 116: 1847-58 PubMed GONUTS page
- ↑ Catena R et al. (2005) Proteolytic cleavage of ALF into alpha- and beta-subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cells. FEBS Lett 579: 3401-10 PubMed GONUTS page
- ↑ Cheng Y et al. (2007) Abnormal sperm in mice lacking the Taf7l gene. Mol Cell Biol 27: 2582-9 PubMed GONUTS page
- ↑ Guermah M et al. (2003) The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis. Mol Cell 12: 991-1001 PubMed GONUTS page
- ↑ Wang K et al. (2006) Regulated expression of TAF1 in 1-cell mouse embryos. Zygote 14: 209-15 PubMed GONUTS page
