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MGI:Tap2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Tap2 ( synonyms: Abcb3, Ham-2, HAM2, MTP2, PSF2, Tap-2 ) | |
| Protein Name(s) | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP), | |
| External Links | ||
| MGI | MGI:98484 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001916 |
positive regulation of T cell mediated cytotoxicity |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001916 |
positive regulation of T cell mediated cytotoxicity |
MGI:MGI:3611636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001916 |
positive regulation of T cell mediated cytotoxicity |
MGI:MGI:50291 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002237 |
response to molecule of bacterial origin |
MGI:MGI:3611636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0002481 |
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent |
MGI:MGI:3611636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0002485 |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent |
MGI:MGI:50291 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002489 |
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0002489 |
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent |
MGI:MGI:50291 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002591 |
positive regulation of antigen processing and presentation of peptide antigen via MHC class I |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0002591 |
positive regulation of antigen processing and presentation of peptide antigen via MHC class I |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
P |
From MGI |
|||
| GO:0005215 |
transporter activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3037219 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005792 |
microsome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
C |
From MGI |
|||
| GO:0006200 |
ATP catabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006200 |
ATP catabolic process |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
P |
From MGI |
|||
| GO:0006200 |
ATP catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006461 |
protein complex assembly |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0015031 |
protein transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0653 |
P |
From MGI |
||
| GO:0015197 |
peptide transporter activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0015421 |
oligopeptide-transporting ATPase activity |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
F |
From MGI |
|||
| GO:0015433 |
peptide antigen-transporting ATPase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015833 |
peptide transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0015833 |
peptide transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0015833 |
peptide transport |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
P |
From MGI |
|||
| GO:0015833 |
peptide transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016887 |
ATPase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0017111 |
nucleoside-triphosphatase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0019060 |
intracellular transport of viral proteins in host cell |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019885 |
antigen processing and presentation of endogenous peptide antigen via MHC class I |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019885 |
antigen processing and presentation of endogenous peptide antigen via MHC class I |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030176 |
integral to endoplasmic reticulum membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0035672 |
oligopeptide transmembrane transport |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
P |
From MGI |
|||
| GO:0042270 |
protection from natural killer cell mediated cytotoxicity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042288 |
MHC class I protein binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042288 |
MHC class I protein binding |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
F |
From MGI |
|||
| GO:0042605 |
peptide antigen binding |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
F |
From MGI |
|||
| GO:0042626 |
ATPase activity, coupled to transmembrane movement of substances |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042824 |
MHC class I peptide loading complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042825 |
TAP complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042825 |
TAP complex |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
C |
From MGI |
|||
| GO:0042825 |
TAP complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043531 |
ADP binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043657 |
host cell |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0046967 |
cytosol to ER transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046968 |
peptide antigen transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046978 |
TAP1 binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046978 |
TAP1 binding |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
F |
From MGI |
|||
| GO:0046978 |
TAP1 binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046978 |
TAP1 binding |
MGI:MGI:5009195 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0046979 |
TAP2 binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046979 |
TAP2 binding |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
F |
From MGI |
|||
| GO:0046980 |
tapasin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046980 |
tapasin binding |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0055085 |
transmembrane transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0055085 |
transmembrane transport |
MGI:MGI:4459044 |
PANTHER:PTHR24221 |
P |
From MGI |
|||
| GO:0055085 |
transmembrane transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
contributes_to |
GO:0042288 |
MHC class I protein binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
||
|
contributes_to |
GO:0042605 |
peptide antigen binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Ugrinovic S et al. (2005) H2-M3 major histocompatibility complex class Ib-restricted CD8 T cells induced by Salmonella enterica serovar Typhimurium infection recognize proteins released by Salmonella serovar Typhimurium. Infect Immun 73: 8002-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Attaya M et al. (1992) Ham-2 corrects the class I antigen-processing defect in RMA-S cells. Nature 355: 647-9 PubMed GONUTS page
- ↑ Lilić M et al. (2004) Association of beta2-microglobulin with the alpha3 domain of H-2Db heavy chain. Immunogenetics 55: 740-7 PubMed GONUTS page
- ↑ Ritz U et al. (2001) Identification of sequences in the human peptide transporter subunit TAP1 required for transporter associated with antigen processing (TAP) function. Int Immunol 13: 31-41 PubMed GONUTS page
