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MGI:Syt1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Syt1 | |
| Protein Name(s) | synaptotagmin I, | |
| External Links | ||
| MGI | MGI:99667 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005215 |
transporter activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005509 |
calcium ion binding |
MGI:MGI:3047044 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3525418 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3688379 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3837083 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005516 |
calmodulin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005543 |
phospholipid binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005544 |
calcium-dependent phospholipid binding |
MGI:MGI:2673870 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005544 |
calcium-dependent phospholipid binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:4879076 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857252 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3525418 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007269 |
neurotransmitter secretion |
MGI:MGI:3047044 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008021 |
synaptic vesicle |
MGI:MGI:3525418 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0008021 |
synaptic vesicle |
MGI:MGI:3613132 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0008021 |
synaptic vesicle |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016079 |
synaptic vesicle exocytosis |
MGI:MGI:4879076 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857252 |
P |
From MGI |
||
| GO:0017158 |
regulation of calcium ion-dependent exocytosis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019905 |
syntaxin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030141 |
secretory granule |
MGI:MGI:2384381 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030276 |
clathrin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030672 |
synaptic vesicle membrane |
MGI:MGI:3042561 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031045 |
dense core granule |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031410 |
cytoplasmic vesicle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0968 |
C |
From MGI |
||
| GO:0042734 |
presynaptic membrane |
MGI:MGI:3047044 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043005 |
neuron projection |
MGI:MGI:3047044 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043229 |
intracellular organelle |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045202 |
synapse |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0770 |
C |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048306 |
calcium-dependent protein binding |
MGI:MGI:3584221 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0050750 |
low-density lipoprotein particle receptor binding |
MGI:MGI:3042677 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0060076 |
excitatory synapse |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Zhang Q et al. (2004) Synaptotagmin IV regulates glial glutamate release. Proc Natl Acad Sci U S A 101: 9441-6 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Lazzell DR et al. (2004) SV2B regulates synaptotagmin 1 by direct interaction. J Biol Chem 279: 52124-31 PubMed GONUTS page
- ↑ Walther K et al. (2004) Functional dissection of the interactions of stonin 2 with the adaptor complex AP-2 and synaptotagmin. Proc Natl Acad Sci U S A 101: 964-9 PubMed GONUTS page
- ↑ Han C et al. (2009) Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with SNARE machinery. J Immunol 182: 2986-96 PubMed GONUTS page
- ↑ Fukuda M (2003) Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans. J Biochem 133: 641-9 PubMed GONUTS page
- ↑ 6.0 6.1 Burgalossi A et al. (2010) SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming. Neuron 68: 473-87 PubMed GONUTS page
- ↑ Fukuda M (2006) Distinct developmental expression of synaptotagmin I and IX in the mouse brain. Neuroreport 17: 179-82 PubMed GONUTS page
- ↑ Quetglas S et al. (2002) Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis. EMBO J 21: 3970-9 PubMed GONUTS page
- ↑ Gitler D et al. (2004) Molecular determinants of synapsin targeting to presynaptic terminals. J Neurosci 24: 3711-20 PubMed GONUTS page
- ↑ Hutt DM et al. (2005) Synaptotagmin VI and VIII and syntaxin 2 are essential for the mouse sperm acrosome reaction. J Biol Chem 280: 20197-203 PubMed GONUTS page
- ↑ Marschang P et al. (2004) Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. Mol Cell Biol 24: 3782-93 PubMed GONUTS page
