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MGI:Syngap1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Syngap1 ( synonyms: Syngap ) | |
| Protein Name(s) | synaptic Ras GTPase activating protein 1 homolog (rat), | |
| External Links | ||
| MGI | MGI:3039785 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005096 |
GTPase activator activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0343 |
F |
From MGI |
||
| GO:0005096 |
GTPase activator activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005097 |
Rab GTPase activator activity |
MGI:MGI:3037621 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3037621 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005543 |
phospholipid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3037621 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:3037621 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4459044 |
PANTHER:PTHR10194 |
C |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007265 |
Ras protein signal transduction |
MGI:MGI:3037621 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007389 |
pattern specification process |
MGI:MGI:3614311 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580631 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:3580530 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580631 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016358 |
dendrite development |
MGI:MGI:3510474 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3511175 |
P |
From MGI |
||
| GO:0017124 |
SH3 domain binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0729 |
F |
From MGI |
||
| GO:0019901 |
protein kinase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001106880 |
F |
From MGI |
||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0031235 |
intrinsic to internal side of plasma membrane |
MGI:MGI:4459044 |
PANTHER:PTHR10194 |
C |
From MGI |
|||
| GO:0032320 |
positive regulation of Ras GTPase activity |
MGI:MGI:4459044 |
PANTHER:PTHR10194 |
P |
From MGI |
|||
| GO:0032851 |
positive regulation of Rab GTPase activity |
MGI:MGI:3037621 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:3590468 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3511175 |
P |
From MGI |
||
| GO:0043113 |
receptor clustering |
MGI:MGI:3575363 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576223 |
P |
From MGI |
||
| GO:0043198 |
dendritic shaft |
MGI:MGI:3614311 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043408 |
regulation of MAPK cascade |
MGI:MGI:3580530 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580631 |
P |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0770 |
C |
From MGI |
||
| GO:0046580 |
negative regulation of Ras protein signal transduction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001106880 |
P |
From MGI |
||
| GO:0046580 |
negative regulation of Ras protein signal transduction |
MGI:MGI:4459044 |
PANTHER:PTHR10194 |
P |
From MGI |
|||
| GO:0048167 |
regulation of synaptic plasticity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001106880 |
P |
From MGI |
||
| GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
MGI:MGI:3576792 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576223 |
P |
From MGI |
||
| GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
MGI:MGI:3580530 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1277959 |
P |
From MGI |
||
| GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
MGI:MGI:3580530 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580631 |
P |
From MGI |
||
| GO:0050771 |
negative regulation of axonogenesis |
MGI:MGI:3037621 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050803 |
regulation of synapse structure and activity |
MGI:MGI:3510474 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3511175 |
P |
From MGI |
||
| GO:0051056 |
regulation of small GTPase mediated signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Tomoda T et al. (2004) Role of Unc51.1 and its binding partners in CNS axon outgrowth. Genes Dev 18: 541-58 PubMed GONUTS page
- ↑ 2.0 2.1 Barnett MW et al. (2006) Synaptic Ras GTPase activating protein regulates pattern formation in the trigeminal system of mice. J Neurosci 26: 1355-65 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Komiyama NH et al. (2002) SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J Neurosci 22: 9721-32 PubMed GONUTS page
- ↑ 4.0 4.1 Vazquez LE et al. (2004) SynGAP regulates spine formation. J Neurosci 24: 8862-72 PubMed GONUTS page
- ↑ Knuesel I et al. (2005) A role for synGAP in regulating neuronal apoptosis. Eur J Neurosci 21: 611-21 PubMed GONUTS page
- ↑ Kim JH et al. (2003) The role of synaptic GTPase-activating protein in neuronal development and synaptic plasticity. J Neurosci 23: 1119-24 PubMed GONUTS page
- ↑ Turcotte K et al. (2005) A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice. J Exp Med 201: 881-90 PubMed GONUTS page
