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MGI:Syne2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Syne2 ( synonyms: D12Ertd777e, Nesp2g, nesprin-2, syne-2 ) | |
| Protein Name(s) | synaptic nuclear envelope 2, | |
| External Links | ||
| MGI | MGI:2449316 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003779 |
actin binding |
MGI:MGI:4888085 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005635 |
nuclear envelope |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
protein_id:AAH42134 |
C |
From MGI |
||
| GO:0005635 |
nuclear envelope |
MGI:MGI:3529743 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005635 |
nuclear envelope |
MGI:MGI:3810041 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3811076 |
C |
From MGI |
||
| GO:0005635 |
nuclear envelope |
MGI:MGI:4454599 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005635 |
nuclear envelope |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005640 |
nuclear outer membrane |
MGI:MGI:4430813 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0496 |
C |
From MGI |
||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0005925 |
focal adhesion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006998 |
nuclear envelope organization |
MGI:MGI:3810041 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3811076 |
P |
From MGI |
||
| GO:0007097 |
nuclear migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007163 |
establishment or maintenance of cell polarity |
MGI:MGI:3810041 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3811076 |
P |
From MGI |
||
| GO:0010761 |
fibroblast migration |
MGI:MGI:3810041 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3811076 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016529 |
sarcoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030018 |
Z disc |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030335 |
positive regulation of cell migration |
MGI:MGI:4888085 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0031022 |
nuclear migration along microfilament |
MGI:MGI:4888085 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0031258 |
lamellipodium membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031527 |
filopodium membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031965 |
nuclear membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031981 |
nuclear lumen |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0034504 |
protein localization to nucleus |
MGI:MGI:3810041 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3811076 |
P |
From MGI |
||
| GO:0034993 |
SUN-KASH complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0044429 |
mitochondrial part |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0051642 |
centrosome localization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051642 |
centrosome localization |
MGI:MGI:4888085 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0090286 |
cytoskeletal anchoring at nuclear membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
colocalizes_with |
GO:0030016 |
myofibril |
MGI:MGI:3529743 |
IDA: Inferred from Direct Assay |
C |
From MGI |
||
|
colocalizes_with |
GO:0030018 |
Z disc |
MGI:MGI:3529743 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Luxton GW et al. (2010) Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement. Science 329: 956-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Zhang Q et al. (2005) Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle. J Cell Sci 118: 673-87 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Lüke Y et al. (2008) Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J Cell Sci 121: 1887-98 PubMed GONUTS page
- ↑ Kim CE et al. (2010) A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. Proc Natl Acad Sci U S A 107: 9861-6 PubMed GONUTS page
- ↑ Stewart-Hutchinson PJ et al. (2008) Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness. Exp Cell Res 314: 1892-905 PubMed GONUTS page
