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MGI:Stxbp3a
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Stxbp3a ( synonyms: Munc-18c, Stxbp3, Sxtbp3 ) | |
| Protein Name(s) | syntaxin binding protein 3A, | |
| External Links | ||
| MGI | MGI:107362 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
MGI:MGI:2387541 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4352814 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4457249 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:4352814 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3573931 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2387541 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:3050225 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:2387541 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3050225 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006887 |
exocytosis |
MGI:MGI:4352814 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3573931 |
P |
From MGI |
||
| GO:0006904 |
vesicle docking involved in exocytosis |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007420 |
brain development |
MGI:MGI:3528117 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3528591 |
P |
From MGI |
||
| GO:0015031 |
protein transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0653 |
P |
From MGI |
||
| GO:0015758 |
glucose transport |
MGI:MGI:2387541 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016192 |
vesicle-mediated transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016323 |
basolateral plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446089 |
C |
From MGI |
||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:3810032 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446089 |
C |
From MGI |
||
| GO:0017075 |
syntaxin-1 binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446089 |
F |
From MGI |
||
| GO:0019905 |
syntaxin binding |
MGI:MGI:2387541 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0019905 |
syntaxin binding |
MGI:MGI:3528117 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0019905 |
syntaxin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446089 |
F |
From MGI |
||
| GO:0019905 |
syntaxin binding |
MGI:MGI:4457249 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0019905 |
syntaxin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0022615 |
protein to membrane docking |
MGI:MGI:4352814 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030073 |
insulin secretion |
MGI:MGI:4352814 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3573931 |
P |
From MGI |
||
| GO:0031091 |
platelet alpha granule |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032868 |
response to insulin stimulus |
MGI:MGI:3528117 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3528591 |
P |
From MGI |
||
| GO:0042581 |
specific granule |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045955 |
negative regulation of calcium ion-dependent exocytosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051291 |
protein heterooligomerization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446089 |
P |
From MGI |
||
| GO:0070527 |
platelet aggregation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070820 |
tertiary granule |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Macaulay SL et al. (2002) Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells. FEBS Lett 528: 154-60 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Oh E & Thurmond DC (2009) Munc18c depletion selectively impairs the sustained phase of insulin release. Diabetes 58: 1165-74 PubMed GONUTS page
- ↑ 3.0 3.1 Ke B et al. (2007) Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis. J Biol Chem 282: 21786-97 PubMed GONUTS page
- ↑ 4.0 4.1 Widberg CH et al. (2003) Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation. J Biol Chem 278: 35093-101 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Kanda H et al. (2005) Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization. J Clin Invest 115: 291-301 PubMed GONUTS page
- ↑ Procino G et al. (2008) AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b. J Cell Sci 121: 2097-106 PubMed GONUTS page
