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MGI:Srr
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Srr | |
| Protein Name(s) | serine racemase, | |
| External Links | ||
| MGI | MGI:1351636 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000287 |
magnesium ion binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
F |
From MGI |
||
| GO:0000287 |
magnesium ion binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003824 |
catalytic activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0021 |
F |
From MGI |
||
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003941 |
L-serine ammonia-lyase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005509 |
calcium ion binding |
MGI:MGI:2183617 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2183617 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:3760217 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005625 |
soluble fraction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
C |
From MGI |
||
| GO:0006520 |
cellular amino acid metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006563 |
L-serine metabolic process |
MGI:MGI:1347751 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006563 |
L-serine metabolic process |
MGI:MGI:1926659 |
ISO: Inferred from Sequence Orthology |
RefSeq:NP_068766 |
P |
From MGI |
||
| GO:0006563 |
L-serine metabolic process |
MGI:MGI:2183617 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006563 |
L-serine metabolic process |
MGI:MGI:3529732 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006563 |
L-serine metabolic process |
MGI:MGI:3769629 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006563 |
L-serine metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
P |
From MGI |
||
| GO:0006563 |
L-serine metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0021 |
P |
From MGI |
||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008721 |
D-serine ammonia-lyase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0009069 |
serine family amino acid metabolic process |
MGI:MGI:3529611 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016594 |
glycine binding |
MGI:MGI:3529732 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0016829 |
lyase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0456 |
F |
From MGI |
||
| GO:0016853 |
isomerase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0413 |
F |
From MGI |
||
| GO:0018114 |
threonine racemase activity |
MGI:MGI:3529611 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030165 |
PDZ domain binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030170 |
pyridoxal phosphate binding |
MGI:MGI:1347751 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0030170 |
pyridoxal phosphate binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
F |
From MGI |
||
| GO:0030170 |
pyridoxal phosphate binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030378 |
serine racemase activity |
MGI:MGI:1347751 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030378 |
serine racemase activity |
MGI:MGI:1926659 |
ISO: Inferred from Sequence Orthology |
RefSeq:NP_068766 |
F |
From MGI |
||
| GO:0030378 |
serine racemase activity |
MGI:MGI:2183617 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030378 |
serine racemase activity |
MGI:MGI:3529611 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030378 |
serine racemase activity |
MGI:MGI:3529732 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030378 |
serine racemase activity |
MGI:MGI:3760217 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030378 |
serine racemase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
F |
From MGI |
||
| GO:0030378 |
serine racemase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:2183617 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
F |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042866 |
pyruvate biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043025 |
neuronal cell body |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045177 |
apical part of cell |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
C |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0051289 |
protein homotetramerization |
MGI:MGI:2183617 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070178 |
D-serine metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_942052 |
P |
From MGI |
||
| GO:0070178 |
D-serine metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070179 |
D-serine biosynthetic process |
MGI:MGI:1347751 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070179 |
D-serine biosynthetic process |
MGI:MGI:1926659 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070179 |
D-serine biosynthetic process |
MGI:MGI:2183617 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070179 |
D-serine biosynthetic process |
MGI:MGI:3529732 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070179 |
D-serine biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Cook SP et al. (2002) Direct calcium binding results in activation of brain serine racemase. J Biol Chem 277: 27782-92 PubMed GONUTS page
- ↑ 2.0 2.1 Mustafa AK et al. (2007) Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. Proc Natl Acad Sci U S A 104: 2950-5 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Wolosker H et al. (1999) Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. Proc Natl Acad Sci U S A 96: 13409-14 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 De Miranda J et al. (2000) Human serine racemase: moleular cloning, genomic organization and functional analysis. Gene 256: 183-8 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Dunlop DS & Neidle A (2005) Regulation of serine racemase activity by amino acids. Brain Res Mol Brain Res 133: 208-14 PubMed GONUTS page
- ↑ Havenar-Daughton C et al. (2006) Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection. J Immunol 176: 3315-9 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Foltyn VN et al. (2005) Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity. J Biol Chem 280: 1754-63 PubMed GONUTS page
