Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Sra1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Sra1 ( synonyms: Srap )
Protein Name(s) steroid receptor RNA activator 1,
External Links
MGI MGI:1344414

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:3054112
PMID:15343387[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003712

transcription cofactor activity

MGI:MGI:1333984
PMID:10199399[2]

ISO: Inferred from Sequence Orthology

EMBL:AF092038

F

From MGI

GO:0003713

transcription coactivator activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_899158

F

From MGI

GO:0003713

transcription coactivator activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HD15

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_899158

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HD15

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:3053242
PMID:15327771[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005831

steroid hormone aporeceptor complex

MGI:MGI:1333984
PMID:10199399[2]

ISO: Inferred from Sequence Orthology

EMBL:AF092038

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:1333984
PMID:10199399[2]

ISO: Inferred from Sequence Orthology

EMBL:AF092038

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HD15

P

From MGI

GO:0008283

cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HD15

P

From MGI

GO:0010861

thyroid hormone receptor activator activity

MGI:MGI:3050934
PMID:15180993[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0016922

ligand-dependent nuclear receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_899158

F

From MGI

GO:0030154

cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HD15

P

From MGI

GO:0030374

ligand-dependent nuclear receptor transcription coactivator activity

MGI:MGI:3053242
PMID:15327771[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0030374

ligand-dependent nuclear receptor transcription coactivator activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_899158

F

From MGI

GO:0030529

ribonucleoprotein complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HD15

C

From MGI

GO:0031252

cell leading edge

MGI:MGI:3701029
PMID:16831833[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3053242
PMID:15327771[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:2000273

positive regulation of receptor activity

MGI:MGI:3050934
PMID:15180993[4]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Masocha W et al. (2004) Cerebral vessel laminins and IFN-gamma define Trypanosoma brucei brucei penetration of the blood-brain barrier. J Clin Invest 114: 689-94 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lanz RB et al. (1999) A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell 97: 17-27 PubMed GONUTS page
  3. 3.0 3.1 3.2 Zhao X et al. (2004) Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator. Mol Cell 15: 549-58 PubMed GONUTS page
  4. 4.0 4.1 Xu B & Koenig RJ (2004) An RNA-binding domain in the thyroid hormone receptor enhances transcriptional activation. J Biol Chem 279: 33051-6 PubMed GONUTS page
  5. Rakeman AS & Anderson KV (2006) Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching. Development 133: 3075-83 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox