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MGI:Spo11

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Spo11
Protein Name(s) sporulation protein, meiosis-specific, SPO11 homolog (S. cerevisiae),
External Links
MGI MGI:1349669

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000238

zygotene

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3027823

P

From MGI

GO:0000781

chromosome, telomeric region

MGI:MGI:4440771
PMID:20336070[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0001541

ovarian follicle development

MGI:MGI:3529751
PMID:15640358[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2178805

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004084
InterPro:IPR002815
InterPro:IPR013049

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002815
InterPro:IPR013049

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002815
InterPro:IPR013049

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005694

chromosome

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002815
InterPro:IPR013049

C

From MGI

GO:0006259

DNA metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002815
InterPro:IPR013049

P

From MGI

GO:0007126

meiosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0469

P

From MGI

GO:0007131

reciprocal meiotic recombination

MGI:MGI:3612347
PMID:16307920[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2178805

P

From MGI

GO:0007141

male meiosis I

MGI:MGI:3719060
PMID:17696610[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2178805

P

From MGI

GO:0007141

male meiosis I

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3027823

P

From MGI

GO:0007286

spermatid development

MGI:MGI:3719060
PMID:17696610[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2178805

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0034502

protein localization to chromosome

MGI:MGI:4457793
PMID:20551173[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2178805

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Soper SF et al. (2008) Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis. Dev Cell 15: 285-97 PubMed GONUTS page
  2. Zalzman M et al. (2010) Zscan4 regulates telomere elongation and genomic stability in ES cells. Nature 464: 858-63 PubMed GONUTS page
  3. Di Giacomo M et al. (2005) Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. Proc Natl Acad Sci U S A 102: 737-42 PubMed GONUTS page
  4. Guillon H et al. (2005) Crossover and noncrossover pathways in mouse meiosis. Mol Cell 20: 563-73 PubMed GONUTS page
  5. 5.0 5.1 Li XC & Schimenti JC (2007) Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. PLoS Genet 3: e130 PubMed GONUTS page
  6. Kumar R et al. (2010) Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. Genes Dev 24: 1266-80 PubMed GONUTS page
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