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MGI:Spen
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Spen ( synonyms: Mint ) | |
| Protein Name(s) | SPEN homolog, transcriptional regulator (Drosophila), | |
| External Links | ||
| MGI | MGI:1891706 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0001085 |
RNA polymerase II transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001191 |
RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003676 |
nucleic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003697 |
single-stranded DNA binding |
MGI:MGI:1890122 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:1890122 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:3584225 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003723 |
RNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0694 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:1890122 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3584225 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1890122 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3584225 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0007219 |
Notch signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0914 |
P |
From MGI |
||
| GO:0017053 |
transcriptional repressor complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:1890122 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3584225 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:1890122 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050769 |
positive regulation of neurogenesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
NOT |
GO:0003677 |
DNA binding |
MGI:MGI:3584225 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Newberry EP et al. (1999) The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter. Biochemistry 38: 10678-90 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Yang X et al. (2005) Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1. J Biol Chem 280: 18710-6 PubMed GONUTS page
