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MGI:Spast
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Spast ( synonyms: Spg4 ) | |
| Protein Name(s) | spastin, | |
| External Links | ||
| MGI | MGI:1858896 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0001578 |
microtubule bundle formation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2447509 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0967 |
C |
From MGI |
||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0256 |
C |
From MGI |
||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005874 |
microtubule |
MGI:MGI:4819643 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006200 |
ATP catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006888 |
ER to Golgi vesicle-mediated transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007109 |
cytokinesis, completion of separation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0008017 |
microtubule binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
P |
From MGI |
||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008568 |
microtubule-severing ATPase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0017111 |
nucleoside-triphosphatase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0034214 |
protein hexamerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043014 |
alpha-tubulin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0048487 |
beta-tubulin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051013 |
microtubule severing |
MGI:MGI:4819643 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051013 |
microtubule severing |
MGI:MGI:4819643 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1921660 |
P |
From MGI |
||
| GO:0051013 |
microtubule severing |
MGI:MGI:4819643 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2683461 |
P |
From MGI |
||
| GO:0051013 |
microtubule severing |
MGI:MGI:4819643 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051013 |
microtubule severing |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051260 |
protein homooligomerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051301 |
cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Charvin D et al. (2003) Mutations of SPG4 are responsible for a loss of function of spastin, an abundant neuronal protein localized in the nucleus. Hum Mol Genet 12: 71-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Lacroix B et al. (2010) Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. J Cell Biol 189: 945-54 PubMed GONUTS page
