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MGI:Spam1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Spam1 ( synonyms: Ph-20 )
Protein Name(s) sperm adhesion molecule 1,
External Links
MGI MGI:109335

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001669

acrosomal vesicle

MGI:MGI:3611697
PMID:16330764[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013785

F

From MGI

GO:0004415

hyalurononglucosaminidase activity

MGI:MGI:2385393
PMID:12065596[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2386404

F

From MGI

GO:0004415

hyalurononglucosaminidase activity

MGI:MGI:3611697
PMID:16330764[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004415

hyalurononglucosaminidase activity

MGI:MGI:3698110
PMID:16925524[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:3611697
PMID:16330764[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005975

carbohydrate metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR018155

P

From MGI

GO:0007155

cell adhesion

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

From MGI

GO:0007338

single fertilization

MGI:MGI:2385393
PMID:12065596[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2386404

P

From MGI

GO:0007342

fusion of sperm to egg plasma membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001439

P

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3698110
PMID:16925524[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0016798

hydrolase activity, acting on glycosyl bonds

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0326

F

From MGI

GO:0031225

anchored to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0336

C

From MGI

GO:0045121

membrane raft

MGI:MGI:3848778
PMID:19144954[4]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Kim E et al. (2005) Identification of a hyaluronidase, Hyal5, involved in penetration of mouse sperm through cumulus mass. Proc Natl Acad Sci U S A 102: 18028-33 PubMed GONUTS page
  2. 2.0 2.1 Baba D et al. (2002) Mouse sperm lacking cell surface hyaluronidase PH-20 can pass through the layer of cumulus cells and fertilize the egg. J Biol Chem 277: 30310-4 PubMed GONUTS page
  3. 3.0 3.1 Reitinger S et al. (2007) Mouse testicular hyaluronidase-like proteins SPAM1 and HYAL5 but not HYALP1 degrade hyaluronan. Biochem J 401: 79-85 PubMed GONUTS page
  4. Miranda PV et al. (2009) Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm. Biol Reprod 80: 897-904 PubMed GONUTS page
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