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MGI:Sox9
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Sox9 | |
| Protein Name(s) | SRY-box containing gene 9, | |
| External Links | ||
| MGI | MGI:98371 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
MGI:MGI:86312 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0001046 |
core promoter sequence-specific DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
MGI:MGI:4950303 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0001158 |
enhancer sequence-specific DNA binding |
MGI:MGI:5284779 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0001501 |
skeletal system development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001502 |
cartilage condensation |
MGI:MGI:2159578 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158693 |
P |
From MGI |
||
| GO:0001502 |
cartilage condensation |
MGI:MGI:2389523 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0001708 |
cell fate specification |
MGI:MGI:2667289 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0001837 |
epithelial to mesenchymal transition |
MGI:MGI:3041362 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0001894 |
tissue homeostasis |
MGI:MGI:4947506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001934 |
positive regulation of protein phosphorylation |
MGI:MGI:3839710 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001934 |
positive regulation of protein phosphorylation |
MGI:MGI:4950303 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001942 |
hair follicle development |
MGI:MGI:3587129 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0002053 |
positive regulation of mesenchymal cell proliferation |
MGI:MGI:3709829 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0002053 |
positive regulation of mesenchymal cell proliferation |
MGI:MGI:4454502 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0002063 |
chondrocyte development |
MGI:MGI:3784676 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0002683 |
negative regulation of immune system process |
MGI:MGI:4947506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0003170 |
heart valve development |
MGI:MGI:4947506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0003179 |
heart valve morphogenesis |
MGI:MGI:3709829 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0003188 |
heart valve formation |
MGI:MGI:3709829 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0003203 |
endocardial cushion morphogenesis |
MGI:MGI:3709802 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0003413 |
chondrocyte differentiation involved in endochondral bone morphogenesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0003415 |
chondrocyte hypertrophy |
MGI:MGI:4950303 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3573967 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:1303256 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3693054 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
F |
From MGI |
||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003705 |
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003705 |
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
MGI:MGI:5284779 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004672 |
protein kinase activity |
MGI:MGI:4950303 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2447911 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2668257 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3839710 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4365886 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5285147 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:4950303 |
IMP: Inferred from Mutant Phenotype |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2183127 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2670853 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2675979 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3051710 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3513641 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3573967 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3583842 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3611673 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3709829 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3776980 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3846269 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4365886 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4367296 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4939090 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4949803 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:5285125 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:5285147 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006334 |
nucleosome assembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006338 |
chromatin remodeling |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2159578 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4367296 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006461 |
protein complex assembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:4939090 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
MGI:MGI:5285125 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007283 |
spermatogenesis |
MGI:MGI:3836884 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0007507 |
heart development |
MGI:MGI:3041362 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0008013 |
beta-catenin binding |
MGI:MGI:4365886 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:3703224 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:3815251 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385469 |
P |
From MGI |
||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:3830946 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0008584 |
male gonad development |
MGI:MGI:2178704 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580900 |
P |
From MGI |
||
| GO:0008584 |
male gonad development |
MGI:MGI:3039994 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0008584 |
male gonad development |
MGI:MGI:3039994 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0008584 |
male gonad development |
MGI:MGI:3836884 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0008584 |
male gonad development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010564 |
regulation of cell cycle process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010628 |
positive regulation of gene expression |
MGI:MGI:3836884 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0010634 |
positive regulation of epithelial cell migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010634 |
positive regulation of epithelial cell migration |
MGI:MGI:5285125 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0014032 |
neural crest cell development |
MGI:MGI:3613316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3041881 |
P |
From MGI |
||
| GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase cascade |
MGI:MGI:4950303 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0016585 |
chromatin remodeling complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0019100 |
male germ-line sex determination |
MGI:MGI:2178704 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580900 |
P |
From MGI |
||
| GO:0019100 |
male germ-line sex determination |
MGI:MGI:3611673 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0019933 |
cAMP-mediated signaling |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:2389523 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0030155 |
regulation of cell adhesion |
MGI:MGI:3795349 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0030198 |
extracellular matrix organization |
MGI:MGI:3709829 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0030238 |
male sex determination |
MGI:MGI:3639791 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104723 |
P |
From MGI |
||
| GO:0030279 |
negative regulation of ossification |
MGI:MGI:4947506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030502 |
negative regulation of bone mineralization |
MGI:MGI:2135696 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158693 |
P |
From MGI |
||
| GO:0030858 |
positive regulation of epithelial cell differentiation |
MGI:MGI:3766658 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0030916 |
otic vesicle formation |
MGI:MGI:3795349 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0031018 |
endocrine pancreas development |
MGI:MGI:3815251 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385469 |
P |
From MGI |
||
| GO:0032331 |
negative regulation of chondrocyte differentiation |
MGI:MGI:2135696 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158693 |
P |
From MGI |
||
| GO:0032332 |
positive regulation of chondrocyte differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032332 |
positive regulation of chondrocyte differentiation |
MGI:MGI:4950303 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0032332 |
positive regulation of chondrocyte differentiation |
MGI:MGI:5285147 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0034236 |
protein kinase A catalytic subunit binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035019 |
somatic stem cell maintenance |
MGI:MGI:4836759 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0035326 |
enhancer binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035326 |
enhancer binding |
MGI:MGI:5142387 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0035622 |
intrahepatic bile duct development |
MGI:MGI:3852603 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0042127 |
regulation of cell proliferation |
MGI:MGI:3587129 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:3587129 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:3703224 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:4950303 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043491 |
protein kinase B signaling cascade |
MGI:MGI:4950303 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:3578585 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:3693054 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0045165 |
cell fate commitment |
MGI:MGI:3578716 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0045595 |
regulation of cell differentiation |
MGI:MGI:3830946 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0045662 |
negative regulation of myoblast differentiation |
MGI:MGI:2670853 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045732 |
positive regulation of protein catabolic process |
MGI:MGI:3839710 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:2670853 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3584225 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4939090 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3584225 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3693054 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:86312 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:1303256 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98367 |
P |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:1859123 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2447911 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2668257 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3573967 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3758399 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:5284779 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:5285147 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:893464 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046533 |
negative regulation of photoreceptor cell differentiation |
MGI:MGI:4368088 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0048709 |
oligodendrocyte differentiation |
MGI:MGI:3693054 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0050679 |
positive regulation of epithelial cell proliferation |
MGI:MGI:4421595 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0050679 |
positive regulation of epithelial cell proliferation |
MGI:MGI:4454502 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0050680 |
negative regulation of epithelial cell proliferation |
MGI:MGI:3766658 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0051216 |
cartilage development |
MGI:MGI:2135696 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158693 |
P |
From MGI |
||
| GO:0060008 |
Sertoli cell differentiation |
MGI:MGI:3039994 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0060009 |
Sertoli cell development |
MGI:MGI:3836884 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0060018 |
astrocyte fate commitment |
MGI:MGI:4368088 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0060041 |
retina development in camera-type eye |
MGI:MGI:4368088 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0060221 |
retinal rod cell differentiation |
MGI:MGI:4368088 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0060350 |
endochondral bone morphogenesis |
MGI:MGI:2135696 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158693 |
P |
From MGI |
||
| GO:0060512 |
prostate gland morphogenesis |
MGI:MGI:3794471 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0060517 |
epithelial cell proliferation involved in prostatic bud elongation |
MGI:MGI:3794471 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0060729 |
intestinal epithelial structure maintenance |
MGI:MGI:3766658 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429649 |
P |
From MGI |
||
| GO:0060784 |
regulation of cell proliferation involved in tissue homeostasis |
MGI:MGI:3830946 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0061036 |
positive regulation of cartilage development |
MGI:MGI:3839710 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0061036 |
positive regulation of cartilage development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0061138 |
morphogenesis of a branching epithelium |
MGI:MGI:4939090 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0070168 |
negative regulation of biomineral tissue development |
MGI:MGI:4947506 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070371 |
ERK1 and ERK2 cascade |
MGI:MGI:5285125 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071260 |
cellular response to mechanical stimulus |
MGI:MGI:5285125 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071300 |
cellular response to retinoic acid |
MGI:MGI:3848572 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071364 |
cellular response to epidermal growth factor stimulus |
MGI:MGI:5285125 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071504 |
cellular response to heparin |
MGI:MGI:5285125 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071560 |
cellular response to transforming growth factor beta stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0072034 |
renal vesicle induction |
MGI:MGI:4939090 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0072197 |
ureter morphogenesis |
MGI:MGI:4939090 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0072289 |
metanephric nephron tubule formation |
MGI:MGI:4939090 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98370 |
P |
From MGI |
||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:3768575 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:3830946 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:3839710 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090103 |
cochlea morphogenesis |
MGI:MGI:4454502 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:0090184 |
positive regulation of kidney development |
MGI:MGI:4939090 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0090190 |
positive regulation of branching involved in ureteric bud morphogenesis |
MGI:MGI:4939090 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:2000020 |
positive regulation of male gonad development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2000138 |
positive regulation of cell proliferation involved in heart morphogenesis |
MGI:MGI:3709829 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385468 |
P |
From MGI |
||
| GO:2000741 |
positive regulation of mesenchymal stem cell differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ng LJ et al. (1997) SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol 183: 108-21 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Ikegami D et al. (2011) Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development 138: 1507-19 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Sumi E et al. (2007) SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cells. Am J Pathol 170: 1854-64 PubMed GONUTS page
- ↑ 4.0 4.1 Bi W et al. (1999) Sox9 is required for cartilage formation. Nat Genet 22: 85-9 PubMed GONUTS page
- ↑ 5.0 5.1 Akiyama H et al. (2002) The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev 16: 2813-28 PubMed GONUTS page
- ↑ Stolt CC et al. (2003) The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev 17: 1677-89 PubMed GONUTS page
- ↑ 7.0 7.1 Akiyama H et al. (2004) Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa. Proc Natl Acad Sci U S A 101: 6502-7 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 Peacock JD et al. (2010) Reduced sox9 function promotes heart valve calcification phenotypes in vivo. Circ Res 106: 712-9 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 Topol L et al. (2009) Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus. J Biol Chem 284: 3323-33 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Vidal VP et al. (2005) Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. Curr Biol 15: 1340-51 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 11.3 11.4 11.5 Lincoln J et al. (2007) Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development. Dev Biol 305: 120-32 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 Trowe MO et al. (2010) Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse. Dev Biol 342: 51-62 PubMed GONUTS page
- ↑ Hargus G et al. (2008) Loss of Sox9 function results in defective chondrocyte differentiation of mouse embryonic stem cells in vitro. Int J Dev Biol 52: 323-32 PubMed GONUTS page
- ↑ Pappas GD et al. (2001) Reelin in the extracellular matrix and dendritic spines of the cortex and hippocampus: a comparison between wild type and heterozygous reeler mice by immunoelectron microscopy. J Neurocytol 30: 413-25 PubMed GONUTS page
- ↑ 15.0 15.1 15.2 Wilson MJ et al. (2005) The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development. J Biol Chem 280: 5917-23 PubMed GONUTS page
- ↑ 16.0 16.1 Lefebvre V et al. (1998) A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J 17: 5718-33 PubMed GONUTS page
- ↑ 17.0 17.1 17.2 17.3 Stolt CC et al. (2006) SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell 11: 697-709 PubMed GONUTS page
- ↑ 18.0 18.1 Huang W et al. (2002) A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene. J Biol Chem 277: 50668-75 PubMed GONUTS page
- ↑ 19.0 19.1 Schepers G et al. (2003) SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro. J Biol Chem 278: 28101-8 PubMed GONUTS page
- ↑ 20.0 20.1 20.2 Ito T et al. (2009) Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol 9: 47 PubMed GONUTS page
- ↑ 21.0 21.1 21.2 21.3 Takigawa Y et al. (2010) The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9. J Cell Sci 123: 3780-8 PubMed GONUTS page
- ↑ Davies SR et al. (2002) Distribution of the transcription factors Sox9, AP-2, and [delta]EF1 in adult murine articular and meniscal cartilage and growth plate. J Histochem Cytochem 50: 1059-65 PubMed GONUTS page
- ↑ 23.0 23.1 23.2 Schmidt K et al. (2003) Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis. J Biol Chem 278: 29769-75 PubMed GONUTS page
- ↑ Sarraj MA et al. (2003) Sox15 is up regulated in the embryonic mouse testis. Gene Expr Patterns 3: 413-7 PubMed GONUTS page
- ↑ Schmahl J et al. (2004) Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. Development 131: 3627-36 PubMed GONUTS page
- ↑ Nakamuta N & Kobayashi S (2004) Expression of p63 in the mouse primordial germ cells. J Vet Med Sci 66: 1365-70 PubMed GONUTS page
- ↑ Ottolenghi C et al. (2005) Foxl2 is required for commitment to ovary differentiation. Hum Mol Genet 14: 2053-62 PubMed GONUTS page
- ↑ 28.0 28.1 Barrionuevo F et al. (2006) Homozygous inactivation of Sox9 causes complete XY sex reversal in mice. Biol Reprod 74: 195-201 PubMed GONUTS page
- ↑ Fauquier T et al. (2008) SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland. Proc Natl Acad Sci U S A 105: 2907-12 PubMed GONUTS page
- ↑ van der Flier LG et al. (2009) Transcription factor achaete scute-like 2 controls intestinal stem cell fate. Cell 136: 903-12 PubMed GONUTS page
- ↑ 31.0 31.1 Nishiyama A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5: 420-33 PubMed GONUTS page
- ↑ 32.0 32.1 32.2 32.3 32.4 32.5 32.6 32.7 32.8 Reginensi A et al. (2011) SOX9 controls epithelial branching by activating RET effector genes during kidney development. Hum Mol Genet 20: 1143-53 PubMed GONUTS page
- ↑ Osorio KM et al. (2011) Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol 193: 235-50 PubMed GONUTS page
- ↑ 34.0 34.1 34.2 34.3 34.4 34.5 34.6 Ling S et al. (2011) An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer. Cancer Res 71: 3812-21 PubMed GONUTS page
- ↑ 35.0 35.1 35.2 35.3 Barrionuevo F et al. (2009) Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev Biol 327: 301-12 PubMed GONUTS page
- ↑ 36.0 36.1 Seymour PA et al. (2007) SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A 104: 1865-70 PubMed GONUTS page
- ↑ 37.0 37.1 Seymour PA et al. (2008) A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol 323: 19-30 PubMed GONUTS page
- ↑ 38.0 38.1 38.2 38.3 Bastide P et al. (2007) Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium. J Cell Biol 178: 635-48 PubMed GONUTS page
- ↑ 39.0 39.1 Vidal VP et al. (2001) Sox9 induces testis development in XX transgenic mice. Nat Genet 28: 216-7 PubMed GONUTS page
- ↑ 40.0 40.1 40.2 Chaboissier MC et al. (2004) Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development 131: 1891-901 PubMed GONUTS page
- ↑ Cheung M et al. (2005) The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell 8: 179-92 PubMed GONUTS page
- ↑ 42.0 42.1 Barrionuevo F et al. (2008) Sox9 is required for invagination of the otic placode in mice. Dev Biol 317: 213-24 PubMed GONUTS page
- ↑ Kim Y et al. (2006) Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination. PLoS Biol 4: e187 PubMed GONUTS page
- ↑ 44.0 44.1 44.2 44.3 Bi W et al. (2001) Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proc Natl Acad Sci U S A 98: 6698-703 PubMed GONUTS page
- ↑ 45.0 45.1 45.2 Mori-Akiyama Y et al. (2007) SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology 133: 539-46 PubMed GONUTS page
- ↑ Scott CE et al. (2010) SOX9 induces and maintains neural stem cells. Nat Neurosci 13: 1181-9 PubMed GONUTS page
- ↑ Huang W et al. (2000) Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer. Mol Cell Biol 20: 4149-58 PubMed GONUTS page
- ↑ Antoniou A et al. (2009) Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology 136: 2325-33 PubMed GONUTS page
- ↑ Meech R et al. (2005) The homeobox transcription factor Barx2 regulates chondrogenesis during limb development. Development 132: 2135-46 PubMed GONUTS page
- ↑ Stolt CC et al. (2005) Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Dev Biol 281: 309-17 PubMed GONUTS page
- ↑ 51.0 51.1 Yang X et al. (2005) Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1. J Biol Chem 280: 18710-6 PubMed GONUTS page
- ↑ Tanaka K et al. (2000) A zinc finger transcription factor, alphaA-crystallin binding protein 1, is a negative regulator of the chondrocyte-specific enhancer of the alpha1(II) collagen gene. Mol Cell Biol 20: 4428-35 PubMed GONUTS page
- ↑ Kim JS et al. (2007) Cytokine-like 1 (Cytl1) regulates the chondrogenesis of mesenchymal cells. J Biol Chem 282: 29359-67 PubMed GONUTS page
- ↑ Bell DM et al. (1997) SOX9 directly regulates the type-II collagen gene. Nat Genet 16: 174-8 PubMed GONUTS page
- ↑ 55.0 55.1 55.2 55.3 Muto A et al. (2009) The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Müller glial cell development in mouse retina. Exp Eye Res 89: 549-58 PubMed GONUTS page
- ↑ Thomsen MK et al. (2010) SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. Cancer Res 70: 979-87 PubMed GONUTS page
- ↑ 57.0 57.1 Thomsen MK et al. (2008) Sox9 is required for prostate development. Dev Biol 316: 302-11 PubMed GONUTS page
- ↑ Williams JA et al. (2009) Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse. Dev Biol 328: 315-27 PubMed GONUTS page
- ↑ Sinner D et al. (2007) Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol 27: 7802-15 PubMed GONUTS page
