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MGI:Sort1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Sort1 ( synonyms: neurotensin receptor 3, Ntr3, Ntsr3, sortilin )
Protein Name(s) sortilin 1,
External Links
MGI MGI:1338015

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001503

ossification

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0892

P

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005764

lysosome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0458

C

From MGI

GO:0005768

endosome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0967

C

From MGI

GO:0005769

early endosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From MGI

GO:0005792

microsome

MGI:MGI:3582104
PMID:15992544[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005792

microsome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O54861

C

From MGI

GO:0005792

microsome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:3582104
PMID:15992544[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O54861

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0005905

coated pit

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006895

Golgi to endosome transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0006897

endocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0007218

neuropeptide signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0008333

endosome to lysosome transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0008624

induction of apoptosis by extracellular signals

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0009986

cell surface

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0010465

nerve growth factor receptor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

F

From MGI

GO:0010468

regulation of gene expression

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0014902

myotube differentiation

MGI:MGI:3777515
PMID:18258592[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0014902

myotube differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O54861

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0016023

cytoplasmic membrane-bounded vesicle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0016050

vesicle organization

MGI:MGI:3582104
PMID:15992544[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016050

vesicle organization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0019899

enzyme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

F

From MGI

GO:0030136

clathrin-coated vesicle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0030140

trans-Golgi network transport vesicle

MGI:MGI:3040541
PMID:15078902[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030379

neurotensin receptor activity, non-G-protein coupled

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

F

From MGI

GO:0030425

dendrite

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O54861

C

From MGI

GO:0032509

endosome transport via multivesicular body sorting pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0032868

response to insulin stimulus

MGI:MGI:3582104
PMID:15992544[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0032868

response to insulin stimulus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0043025

neuronal cell body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O54861

C

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O54861

C

From MGI

GO:0046323

glucose import

MGI:MGI:3582104
PMID:15992544[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0046323

glucose import

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0048011

nerve growth factor receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0048227

plasma membrane to endosome transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI

GO:0048406

nerve growth factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

F

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

C

From MGI

GO:0051005

negative regulation of lipoprotein lipase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99523

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Shi J & Kandror KV (2005) Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes. Dev Cell 9: 99-108 PubMed GONUTS page
  2. Ariga M et al. (2008) Functional role of sortilin in myogenesis and development of insulin-responsive glucose transport system in C2C12 myocytes. J Biol Chem 283: 10208-20 PubMed GONUTS page
  3. Seaman MN (2004) Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. J Cell Biol 165: 111-22 PubMed GONUTS page
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