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MGI:Sorbs3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Sorbs3 ( synonyms: Sh3d4, SH3P3, vinexin alpha, vinexin beta )
Protein Name(s) sorbin and SH3 domain containing 3,
External Links
MGI MGI:700013

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3579939
PMID:15734736[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:97858

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3579939
PMID:15734736[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0005515

protein binding

MGI:MGI:3608171
PMID:15836771[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q99N57

F

From MGI

GO:0005634

nucleus

MGI:MGI:1349785
PMID:9885244[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:3579939
PMID:15734736[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1349785
PMID:9885244[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3579939
PMID:15734736[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3608171
PMID:15836771[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0005925

focal adhesion

MGI:MGI:1349785
PMID:9885244[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:3579939
PMID:15734736[1]

IPI: Inferred from Physical Interaction

UniProtKB:P13631

F

From MGI

GO:0017166

vinculin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60504

F

From MGI

GO:0030054

cell junction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From MGI

GO:0031589

cell-substrate adhesion

MGI:MGI:1349785
PMID:9885244[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043410

positive regulation of MAPK cascade

MGI:MGI:3608171
PMID:15836771[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043410

positive regulation of MAPK cascade

MGI:MGI:3608171
PMID:15836771[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3611214

P

From MGI

GO:0051496

positive regulation of stress fiber assembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60504

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Bour G et al. (2005) Vinexin beta interacts with the non-phosphorylated AF-1 domain of retinoid receptor gamma (RARgamma) and represses RARgamma-mediated transcription. J Biol Chem 280: 17027-37 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Matsuyama M et al. (2005) A novel isoform of Vinexin, Vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad. Genes Cells 10: 421-34 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Kioka N et al. (1999) Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization. J Cell Biol 144: 59-69 PubMed GONUTS page
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