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MGI:Slit3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Slit3 | |
| Protein Name(s) | slit homolog 3 (Drosophila), | |
| External Links | ||
| MGI | MGI:1315202 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0008285 |
negative regulation of cell proliferation |
J:141875 PMID:18829537[1][ |
IGI: Inferred from Genetic Interaction |
MGI:1315205
|
P |
complete | ||
| GO:0010629 |
negative regulation of gene expression |
J:141875 PMID:18829537[1][ |
IGI: Inferred from Genetic Interaction |
MGI:1315205
|
P |
complete | ||
| GO:0005102 |
receptor binding |
MGI:MGI:2678272 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005509 |
calcium ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005615 |
extracellular space |
MGI:MGI:2678272 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0007411 |
axon guidance |
MGI:MGI:2678272 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007411 |
axon guidance |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:3819920 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1315205 |
P |
From MGI |
||
| GO:0009887 |
organ morphogenesis |
MGI:MGI:2678879 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2679499 |
P |
From MGI |
||
| GO:0009887 |
organ morphogenesis |
MGI:MGI:3041390 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2179460 |
P |
From MGI |
||
| GO:0010629 |
negative regulation of gene expression |
MGI:MGI:3819920 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1315205 |
P |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030308 |
negative regulation of cell growth |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035385 |
Roundabout signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048495 |
Roundabout binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0048846 |
axon extension involved in axon guidance |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050919 |
negative chemotaxis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070100 |
negative regulation of chemokine-mediated signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
colocalizes_with |
GO:0005739 |
mitochondrion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Marlow R et al. (2008) SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium. Cancer Res 68: 7819-27 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Knöll B et al. (2003) On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion. Development 130: 5073-82 PubMed GONUTS page
- ↑ Liu J et al. (2003) Congenital diaphragmatic hernia, kidney agenesis and cardiac defects associated with Slit3-deficiency in mice. Mech Dev 120: 1059-70 PubMed GONUTS page
- ↑ Long H et al. (2004) Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron 42: 213-23 PubMed GONUTS page
