Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Slc9a1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Slc9a1 ( synonyms: antiporter, Apnh, Nhe1 )
Protein Name(s) solute carrier family 9 (sodium/hydrogen exchanger), member 1,
External Links
MGI MGI:102462

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001101

response to acid

MGI:MGI:1353365
PMID:10673550[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429323

P

From MGI

GO:0005516

calmodulin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0112

F

From MGI

GO:0005622

intracellular

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

C

From MGI

GO:0005624

membrane fraction

MGI:MGI:2655940
PMID:12619893[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006811

ion transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0406

P

From MGI

GO:0006812

cation transport

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006153
InterPro:IPR018422

P

From MGI

GO:0006814

sodium ion transport

MGI:MGI:2446396
PMID:10666043[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006885

regulation of pH

MGI:MGI:1353365
PMID:10673550[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429323

P

From MGI

GO:0006885

regulation of pH

MGI:MGI:2446396
PMID:10666043[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007243

intracellular protein kinase cascade

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

F

From MGI

GO:0010447

response to acidity

MGI:MGI:1353365
PMID:10673550[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429323

P

From MGI

GO:0014070

response to organic cyclic compound

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

P

From MGI

GO:0015297

antiporter activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0050

F

From MGI

GO:0015299

solute:hydrogen antiporter activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006153
InterPro:IPR018422

F

From MGI

GO:0015385

sodium:hydrogen antiporter activity

MGI:MGI:2446396
PMID:10666043[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0015385

sodium:hydrogen antiporter activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

F

From MGI

GO:0015992

proton transport

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006153
InterPro:IPR018422

P

From MGI

GO:0015992

proton transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006153
InterPro:IPR018422
InterPro:IPR001970
InterPro:IPR004709

C

From MGI

GO:0016323

basolateral plasma membrane

MGI:MGI:2446396
PMID:10666043[3]

TAS: Traceable Author Statement

C

From MGI

GO:0016323

basolateral plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

C

From MGI

GO:0034220

ion transmembrane transport

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006153
InterPro:IPR018422

P

From MGI

GO:0045121

membrane raft

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

C

From MGI

GO:0045768

positive regulation of anti-apoptosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26431

P

From MGI

GO:0055085

transmembrane transport

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006153
InterPro:IPR004709

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Nguyen HV et al. (2000) Muscarinic receptor-induced acidification in sublingual mucous acinar cells: loss of pH recovery in Na+-H+ exchanger-1 deficient mice. J Physiol 523 Pt 1: 139-46 PubMed GONUTS page
  2. Rieder CV & Fliegel L (2003) Transcriptional regulation of Na+/H+ exchanger expression in the intact mouse. Mol Cell Biochem 243: 87-95 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Praetorius J et al. (2000) NHE1, NHE2, and NHE3 contribute to regulation of intracellular pH in murine duodenal epithelial cells. Am J Physiol Gastrointest Liver Physiol 278: G197-206 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox