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MGI:Skil

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Skil ( synonyms: Skir, sno-dE3, SnoN, SnoN2 )
Protein Name(s) SKI-like,
External Links
MGI MGI:106203

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:1858539
PMID:10811619[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3530729
PMID:15677329[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:98834

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3797158
PMID:18212064[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:98834
MGI:MGI:98725

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

P

From MGI

GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009061

F

From MGI

GO:0001669

acrosomal vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001057072

C

From MGI

GO:0001825

blastocyst formation

MGI:MGI:1858539
PMID:10811619[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2387096

P

From MGI

GO:0002260

lymphocyte homeostasis

MGI:MGI:1858539
PMID:10811619[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2387096

P

From MGI

GO:0003682

chromatin binding

MGI:MGI:3528807
PMID:15657445[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003714

transcription corepressor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

F

From MGI

GO:0005515

protein binding

MGI:MGI:3720408
PMID:17215516[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q9R1K5

F

From MGI

GO:0005634

nucleus

MGI:MGI:3797158
PMID:18212064[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001057072

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4459044

PANTHER:PTHR10005

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

C

From MGI

GO:0007050

cell cycle arrest

MGI:MGI:1858539
PMID:10811619[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2387096

P

From MGI

GO:0007179

transforming growth factor beta receptor signaling pathway

MGI:MGI:3797158
PMID:18212064[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:98725
MGI:MGI:98834

P

From MGI

GO:0007519

skeletal muscle tissue development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

P

From MGI

GO:0016605

PML body

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

C

From MGI

GO:0019904

protein domain specific binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

F

From MGI

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:3530729
PMID:15677329[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

P

From MGI

GO:0032403

protein complex binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

F

From MGI

GO:0042981

regulation of apoptotic process

MGI:MGI:1858539
PMID:10811619[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2387096

P

From MGI

GO:0045596

negative regulation of cell differentiation

MGI:MGI:3720408
PMID:17215516[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046332

SMAD binding

MGI:MGI:4459044

PANTHER:PTHR10005

F

From MGI

GO:0046332

SMAD binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

F

From MGI

GO:0050772

positive regulation of axonogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001057072

P

From MGI

GO:0050772

positive regulation of axonogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

P

From MGI

GO:0070207

protein homotrimerization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

P

From MGI

GO:0070208

protein heterotrimerization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

P

From MGI

GO:0070306

lens fiber cell differentiation

MGI:MGI:3720408
PMID:17215516[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0070848

response to growth factor stimulus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P12757

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Shinagawa T et al. (2000) The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice. EMBO J 19: 2280-91 PubMed GONUTS page
  2. 2.0 2.1 Letts VA et al. (2005) A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice. Proc Natl Acad Sci U S A 102: 2123-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 Wilkinson DS et al. (2008) Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression. Mol Cell Biol 28: 1988-98 PubMed GONUTS page
  4. Wilkinson DS et al. (2005) A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene. Mol Cell Biol 25: 1200-12 PubMed GONUTS page
  5. 5.0 5.1 5.2 Wu G et al. (2007) The anaphase-promoting complex coordinates initiation of lens differentiation. Mol Biol Cell 18: 1018-29 PubMed GONUTS page
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