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MGI:Siva1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Siva1 ( synonyms: CD27bp )
Protein Name(s) SIVA1, apoptosis-inducing factor,
External Links
MGI MGI:1353606

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001618

viral receptor activity

MGI:MGI:3700425
PMID:11601913[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005164

tumor necrosis factor receptor binding

MGI:MGI:3696501
PMID:12478477[2]

IPI: Inferred from Physical Interaction

UniProtKB:O35714
UniProtKB:P47741

F

From MGI

GO:0005175

CD27 receptor binding

MGI:MGI:3696501
PMID:12478477[2]

IPI: Inferred from Physical Interaction

UniProtKB:P41272

F

From MGI

GO:0005175

CD27 receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

F

From MGI

GO:0005515

protein binding

MGI:MGI:3687722
PMID:9692890[3]

IPI: Inferred from Physical Interaction

UniProtKB:P41272

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005654

nucleoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

C

From MGI

GO:0006915

apoptotic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0053

P

From MGI

GO:0006917

induction of apoptosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

P

From MGI

GO:0006924

activation-induced cell death of T cells

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

P

From MGI

GO:0008270

zinc ion binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

F

From MGI

GO:0008635

activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

P

From MGI

GO:0008656

cysteine-type endopeptidase activator activity involved in apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

F

From MGI

GO:0009615

response to virus

MGI:MGI:3700425
PMID:11601913[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0019987

negative regulation of anti-apoptosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

P

From MGI

GO:0032088

negative regulation of NF-kappaB transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15304

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Henke A et al. (2001) The apoptotic capability of coxsackievirus B3 is influenced by the efficient interaction between the capsid protein VP2 and the proapoptotic host protein Siva. Virology 289: 15-22 PubMed GONUTS page
  2. 2.0 2.1 Spinicelli S et al. (2002) GITR interacts with the pro-apoptotic protein Siva and induces apoptosis. Cell Death Differ 9: 1382-4 PubMed GONUTS page
  3. Gravestein LA et al. (1998) The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2. Eur J Immunol 28: 2208-16 PubMed GONUTS page
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