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MGI:Sirpa

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Sirpa ( synonyms: Bit, CD172a, P84, Ptpns1, SHPS-1, SIRP )
Protein Name(s) signal-regulatory protein alpha,
External Links
MGI MGI:108563

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

MGI:MGI:2177910
PMID:11895767[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9R1X3

F

From MGI

GO:0005515

protein binding

MGI:MGI:2680858
PMID:14634079[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q61735

F

From MGI

GO:0005515

protein binding

MGI:MGI:2682475
PMID:14662855[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q8K4V9

F

From MGI

GO:0005887

integral to plasma membrane

MGI:MGI:2680858
PMID:14634079[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006910

phagocytosis, recognition

MGI:MGI:2680858
PMID:14634079[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006911

phagocytosis, engulfment

MGI:MGI:2680858
PMID:14634079[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006928

cellular component movement

MGI:MGI:2388975
PMID:11118207[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388979

P

From MGI

GO:0007010

cytoskeleton organization

MGI:MGI:2388975
PMID:11118207[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388979

P

From MGI

GO:0007015

actin filament organization

MGI:MGI:2388975
PMID:11118207[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388979

P

From MGI

GO:0007160

cell-matrix adhesion

MGI:MGI:2388975
PMID:11118207[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388979

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016477

cell migration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97710

P

From MGI

GO:0017124

SH3 domain binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0729

F

From MGI

GO:0045309

protein phosphorylated amino acid binding

MGI:MGI:2429819
PMID:12393607[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q9D3N6

F

From MGI

GO:0050766

positive regulation of phagocytosis

MGI:MGI:2680858
PMID:14634079[2]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Yu WM et al. (2002) Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration. Blood 99: 2351-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Tada K et al. (2003) Tethering of apoptotic cells to phagocytes through binding of CD47 to Src homology 2 domain-bearing protein tyrosine phosphatase substrate-1. J Immunol 171: 5718-26 PubMed GONUTS page
  3. Chung DH et al. (2003) CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation. J Immunol 171: 6541-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Inagaki K et al. (2000) SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility. EMBO J 19: 6721-31 PubMed GONUTS page
  5. Washington AV et al. (2002) Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster. Blood 100: 3822-4 PubMed GONUTS page
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