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MGI:Sigirr
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Sigirr ( synonyms: Sigirr, Tir8 ) | |
| Protein Name(s) | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, | |
| External Links | ||
| MGI | MGI:1344402 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001960 |
negative regulation of cytokine-mediated signaling pathway |
MGI:MGI:2673012 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004888 |
transmembrane signaling receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0006953 |
acute-phase response |
MGI:MGI:2673012 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0031224 |
intrinsic to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045079 |
negative regulation of chemokine biosynthetic process |
MGI:MGI:2673012 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045087 |
innate immune response |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Wald D et al. (2003) SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol 4: 920-7 PubMed GONUTS page
