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MGI:Siah1a
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Siah1a ( synonyms: Sinh1a ) | |
| Protein Name(s) | seven in absentia 1A, | |
| External Links | ||
| MGI | MGI:108064 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:2176683 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
F |
From MGI |
||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4441266 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2653684 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005769 |
early endosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
C |
From MGI |
||
| GO:0005829 |
cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
C |
From MGI |
||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0053 |
P |
From MGI |
||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007141 |
male meiosis I |
MGI:MGI:2176683 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183245 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007283 |
spermatogenesis |
MGI:MGI:2176683 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183245 |
P |
From MGI |
||
| GO:0008022 |
protein C-terminus binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
F |
From MGI |
||
| GO:0008022 |
protein C-terminus binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:4441266 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0009791 |
post-embryonic development |
MGI:MGI:2176683 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183245 |
P |
From MGI |
||
| GO:0016567 |
protein ubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016874 |
ligase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0436 |
F |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030163 |
protein catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030877 |
beta-catenin destruction complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031648 |
protein destabilization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
P |
From MGI |
||
| GO:0040014 |
regulation of multicellular organism growth |
MGI:MGI:2176683 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2183245 |
P |
From MGI |
||
| GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
P |
From MGI |
||
| GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
MGI:MGI:4441266 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4441266 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043161 |
proteasomal ubiquitin-dependent protein catabolic process |
MGI:MGI:4441266 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_543181 |
P |
From MGI |
||
| GO:2001244 |
positive regulation of intrinsic apoptotic signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Dickins RA et al. (2002) The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice. Mol Cell Biol 22: 2294-303 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 House CM et al. (2006) Elucidation of the substrate binding site of Siah ubiquitin ligase. Structure 14: 695-701 PubMed GONUTS page
- ↑ Park TJ et al. (2003) Inhibition of ubiquitin ligase Siah-1A by disabled-1. Biochem Biophys Res Commun 302: 671-8 PubMed GONUTS page
