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MGI:Sh3pxd2b
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Sh3pxd2b ( synonyms: Fad49, Tsk4 ) | |
| Protein Name(s) | SH3 and PX domains 2B, | |
| External Links | ||
| MGI | MGI:2442062 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001501 |
skeletal system development |
MGI:MGI:4439252 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001501 |
skeletal system development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001654 |
eye development |
MGI:MGI:4439252 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001654 |
eye development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0002102 |
podosome |
MGI:MGI:4365313 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0002102 |
podosome |
MGI:MGI:4943661 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3826299 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4365313 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4943661 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006801 |
superoxide metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007154 |
cell communication |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007507 |
heart development |
MGI:MGI:4439252 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007507 |
heart development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010314 |
phosphatidylinositol-5-phosphate binding |
MGI:MGI:3826299 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0022617 |
extracellular matrix disassembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0032266 |
phosphatidylinositol-3-phosphate binding |
MGI:MGI:3826299 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0035091 |
phosphatidylinositol binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0042169 |
SH2 domain binding |
MGI:MGI:3826299 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0045600 |
positive regulation of fat cell differentiation |
MGI:MGI:3826299 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060348 |
bone development |
MGI:MGI:4439252 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060348 |
bone development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060612 |
adipose tissue development |
MGI:MGI:4439252 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070273 |
phosphatidylinositol-4-phosphate binding |
MGI:MGI:3826299 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0071800 |
podosome assembly |
MGI:MGI:4943661 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0072657 |
protein localization in membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0080025 |
phosphatidylinositol-3,5-bisphosphate binding |
MGI:MGI:3826299 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Iqbal Z et al. (2010) Disruption of the podosome adaptor protein TKS4 (SH3PXD2B) causes the skeletal dysplasia, eye, and cardiac abnormalities of Frank-Ter Haar Syndrome. Am J Hum Genet 86: 254-61 PubMed GONUTS page
- ↑ 2.0 2.1 Mao M et al. (2009) The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development. Mamm Genome 20: 462-75 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Buschman MD et al. (2009) The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation. Mol Biol Cell 20: 1302-11 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Hishida T et al. (2008) A novel gene, fad49, plays a crucial role in the immediate early stage of adipocyte differentiation via involvement in mitotic clonal expansion. FEBS J 275: 5576-88 PubMed GONUTS page
