![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Sh2d1b2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Sh2d1b2 ( synonyms: Eat2b, Ert, Sh2d1c ) | |
| Protein Name(s) | SH2 domain protein 1B2, | |
| External Links | ||
| MGI | MGI:3622649 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
MGI:MGI:3618579 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q9QUM4 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3639618 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3836377 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005575 |
cellular component |
MGI:MGI:2156816 |
ND: No biological Data available |
C |
From MGI |
|||
| GO:0018108 |
peptidyl-tyrosine phosphorylation |
MGI:MGI:3639618 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032814 |
regulation of natural killer cell activation |
MGI:MGI:3836377 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1922595 |
P |
From MGI |
||
| GO:0045953 |
negative regulation of natural killer cell mediated cytotoxicity |
MGI:MGI:3639618 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3641175 |
P |
From MGI |
||
| GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
MGI:MGI:3618579 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Calpe S et al. (2006) Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters. Immunogenetics 58: 15-25 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Roncagalli R et al. (2005) Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Nat Immunol 6: 1002-10 PubMed GONUTS page
- ↑ 3.0 3.1 Cruz-Munoz ME et al. (2009) Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function. Nat Immunol 10: 297-305 PubMed GONUTS page