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MGI:Sh2d1b2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Sh2d1b2 ( synonyms: Eat2b, Ert, Sh2d1c )
Protein Name(s) SH2 domain protein 1B2,
External Links
MGI MGI:3622649

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

MGI:MGI:3618579
PMID:16425036[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QUM4
UniProtKB:P08103
UniProtKB:P06240
UniProtKB:P25911
UniProtKB:P14234
UniProtKB:P39688

F

From MGI

GO:0005515

protein binding

MGI:MGI:3639618
PMID:16127454[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q07763

F

From MGI

GO:0005515

protein binding

MGI:MGI:3836377
PMID:19151721[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q8BHK6

F

From MGI

GO:0005575

cellular component

MGI:MGI:2156816

ND: No biological Data available

C

From MGI

GO:0018108

peptidyl-tyrosine phosphorylation

MGI:MGI:3639618
PMID:16127454[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032814

regulation of natural killer cell activation

MGI:MGI:3836377
PMID:19151721[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:1922595

P

From MGI

GO:0045953

negative regulation of natural killer cell mediated cytotoxicity

MGI:MGI:3639618
PMID:16127454[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3641175

P

From MGI

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

MGI:MGI:3618579
PMID:16425036[1]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Calpe S et al. (2006) Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters. Immunogenetics 58: 15-25 PubMed GONUTS page
  2. 2.0 2.1 2.2 Roncagalli R et al. (2005) Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Nat Immunol 6: 1002-10 PubMed GONUTS page
  3. 3.0 3.1 Cruz-Munoz ME et al. (2009) Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function. Nat Immunol 10: 297-305 PubMed GONUTS page
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