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MGI:Sh2d1a

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Sh2d1a ( synonyms: Duncan disease homolog, SAP )
Protein Name(s) SH2 domain protein 1A,
External Links
MGI MGI:1328352

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005070

SH3/SH2 adaptor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017289

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60880

C

From MGI

GO:0006959

humoral immune response

MGI:MGI:3040770
PMID:12529646[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388241

P

From MGI

GO:0006968

cellular defense response

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017289

P

From MGI

GO:0007267

cell-cell signaling

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60880

P

From MGI

GO:0009967

positive regulation of signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017289

P

From MGI

GO:0045954

positive regulation of natural killer cell mediated cytotoxicity

MGI:MGI:3639618
PMID:16127454[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3575311

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Crotty S et al. (2003) SAP is required for generating long-term humoral immunity. Nature 421: 282-7 PubMed GONUTS page
  2. Roncagalli R et al. (2005) Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor. Nat Immunol 6: 1002-10 PubMed GONUTS page
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