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MGI:Sfrp5

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Sfrp5 ( synonyms: SARP3 )
Protein Name(s) secreted frizzled-related sequence protein 5,
External Links
MGI MGI:1860298

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001944

vasculature development

MGI:MGI:4459044

PANTHER:PTHR11309

P

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4459044

PANTHER:PTHR11309

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4459044

PANTHER:PTHR11309

C

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:4459044

PANTHER:PTHR11309

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007420

brain development

MGI:MGI:4459044

PANTHER:PTHR11309

P

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q5T4F7

P

From MGI

GO:0008406

gonad development

MGI:MGI:4459044

PANTHER:PTHR11309

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

From MGI

GO:0017147

Wnt-protein binding

MGI:MGI:4459044

PANTHER:PTHR11309

F

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030165

PDZ domain binding

MGI:MGI:4459044

PANTHER:PTHR11309

F

From MGI

GO:0030178

negative regulation of Wnt receptor signaling pathway

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q9XSC1

P

From MGI

GO:0035121

tail morphogenesis

MGI:MGI:3701561
PMID:16700072[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:108078

P

From MGI

GO:0035414

negative regulation of catenin import into nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q5T4F7

P

From MGI

GO:0042813

Wnt-activated receptor activity

MGI:MGI:4459044

PANTHER:PTHR11309

F

From MGI

GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q5T4F7

P

From MGI

GO:0043508

negative regulation of JUN kinase activity

MGI:MGI:3839161
PMID:19300477[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:892014
MGI:MGI:108078

P

From MGI

GO:0048546

digestive tract morphogenesis

MGI:MGI:3839161
PMID:19300477[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:892014
MGI:MGI:2135272
MGI:MGI:108078

P

From MGI

GO:0051898

negative regulation of protein kinase B signaling cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q5T4F7

P

From MGI

GO:0060028

convergent extension involved in axis elongation

MGI:MGI:3793375
PMID:18257070[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:108078
MGI:MGI:892014

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:4459044

PANTHER:PTHR11309

P

From MGI

GO:0090090

negative regulation of canonical Wnt receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q5T4F7

P

From MGI

GO:0090175

regulation of establishment of planar polarity

MGI:MGI:3839161
PMID:19300477[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:892014
MGI:MGI:2135272
MGI:MGI:108078

P

From MGI

GO:0090179

planar cell polarity pathway involved in neural tube closure

MGI:MGI:3793375
PMID:18257070[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:892014
MGI:MGI:2135272
MGI:MGI:108078

P

From MGI

GO:2000041

negative regulation of planar cell polarity pathway involved in axis elongation

MGI:MGI:3793375
PMID:18257070[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:892014
MGI:MGI:2135272
MGI:MGI:108078

P

From MGI

GO:2000057

negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q5T4F7

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Cox S et al. (2006) Sexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian duct. Mol Reprod Dev 73: 1008-16 PubMed GONUTS page
  2. 2.0 2.1 2.2 Matsuyama M et al. (2009) Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium. PLoS Genet 5: e1000427 PubMed GONUTS page
  3. 3.0 3.1 3.2 Satoh W et al. (2008) Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse. Genesis 46: 92-103 PubMed GONUTS page
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