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MGI:Selp
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Selp ( synonyms: CD62P, Grmp, P-selectin ) | |
| Protein Name(s) | selectin, platelet, | |
| External Links | ||
| MGI | MGI:98280 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001530 |
lipopolysaccharide binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001948 |
glycoprotein binding |
MGI:MGI:3757618 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0002687 |
positive regulation of leukocyte migration |
MGI:MGI:3814295 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98278 |
P |
From MGI |
||
| GO:0002687 |
positive regulation of leukocyte migration |
MGI:MGI:3814295 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0002691 |
regulation of cellular extravasation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3757618 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:67959 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:85772 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006954 |
inflammatory response |
MGI:MGI:2181381 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857245 |
P |
From MGI |
||
| GO:0006954 |
inflammatory response |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0130 |
P |
From MGI |
||
| GO:0007155 |
cell adhesion |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007157 |
heterophilic cell-cell adhesion |
MGI:MGI:3757617 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007157 |
heterophilic cell-cell adhesion |
MGI:MGI:3757618 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007159 |
leukocyte cell-cell adhesion |
MGI:MGI:3757617 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007159 |
leukocyte cell-cell adhesion |
MGI:MGI:3757618 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007159 |
leukocyte cell-cell adhesion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008201 |
heparin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:3757618 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:3814295 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:3849361 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0010572 |
positive regulation of platelet activation |
MGI:MGI:3838274 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:2181381 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:3701917 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016337 |
cell-cell adhesion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030246 |
carbohydrate binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0031092 |
platelet alpha granule membrane |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0033691 |
sialic acid binding |
MGI:MGI:3757618 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0033691 |
sialic acid binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042806 |
fucose binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043499 |
eukaryotic cell surface binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045785 |
positive regulation of cell adhesion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048306 |
calcium-dependent protein binding |
MGI:MGI:67959 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0048514 |
blood vessel morphogenesis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050900 |
leukocyte migration |
MGI:MGI:3513576 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857245 |
P |
From MGI |
||
| GO:0050900 |
leukocyte migration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050901 |
leukocyte tethering or rolling |
MGI:MGI:3701917 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857245 |
P |
From MGI |
||
| GO:0070492 |
oligosaccharide binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0071354 |
cellular response to interleukin-6 |
MGI:MGI:1195834 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Aigner S et al. (1995) Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin. Int Immunol 7: 1557-65 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Mullaly SC & Kubes P (2006) The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands. J Immunol 177: 8154-63 PubMed GONUTS page
- ↑ 3.0 3.1 Sammar M et al. (1994) Heat-stable antigen (CD24) as ligand for mouse P-selectin. Int Immunol 6: 1027-36 PubMed GONUTS page
- ↑ Sammar M et al. (1997) Heat-stable antigen (mouse CD24) in the brain: dual but distinct interaction with P-selectin and L1. Biochim Biophys Acta 1337: 287-94 PubMed GONUTS page
- ↑ 5.0 5.1 Mayadas TN et al. (1993) Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell 74: 541-54 PubMed GONUTS page
- ↑ 6.0 6.1 Ruppert M et al. (1995) The L1 adhesion molecule is a cellular ligand for VLA-5. J Cell Biol 131: 1881-91 PubMed GONUTS page
- ↑ Stone EL et al. (2009) Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol 29: 3770-82 PubMed GONUTS page
- ↑ Ståhl AL et al. (2006) Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome. Blood 108: 167-76 PubMed GONUTS page
- ↑ 9.0 9.1 Dole VS et al. (2005) Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin. Blood 106: 2334-9 PubMed GONUTS page
- ↑ Fernekorn U et al. (2004) Functional involvement of P-selectin and MAdCAM-1 in the recruitment of alpha4beta7-integrin-expressing monocyte-like cells to the pregnant mouse uterus. Eur J Immunol 34: 3423-33 PubMed GONUTS page
- ↑ Peterson RS et al. (1997) The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives. Mech Dev 69: 53-69 PubMed GONUTS page
