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MGI:Scnn1g

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Scnn1g ( synonyms: ENaC gamma )
Protein Name(s) sodium channel, nonvoltage-gated 1 gamma,
External Links
MGI MGI:104695

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005216

ion channel activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0407

F

From MGI

GO:0005624

membrane fraction

MGI:MGI:3761956
PMID:17715136[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006811

ion transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0406

P

From MGI

GO:0006814

sodium ion transport

MGI:MGI:1341933
PMID:10409305[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006814

sodium ion transport

MGI:MGI:3761956
PMID:17715136[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101782
MGI:MGI:104696

P

From MGI

GO:0006814

sodium ion transport

MGI:MGI:3796353
PMID:16941024[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:101782
MGI:MGI:104696

P

From MGI

GO:0006814

sodium ion transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P37091

P

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3761956
PMID:17715136[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009986

cell surface

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P37091

C

From MGI

GO:0015280

ligand-gated sodium channel activity

MGI:MGI:1341933
PMID:10409305[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0015280

ligand-gated sodium channel activity

MGI:MGI:3761956
PMID:17715136[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101782
MGI:MGI:104696

F

From MGI

GO:0015280

ligand-gated sodium channel activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P37091

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001873
InterPro:IPR020903

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1341933
PMID:10409305[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016324

apical plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P37091

C

From MGI

GO:0034220

ion transmembrane transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0407

P

From MGI

GO:0034706

sodium channel complex

MGI:MGI:3761956
PMID:17715136[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101782
MGI:MGI:104696

C

From MGI

GO:0035313

wound healing, spreading of epidermal cells

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P37091

P

From MGI

GO:0035725

sodium ion transmembrane transport

MGI:MGI:1341933
PMID:10409305[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0035725

sodium ion transmembrane transport

MGI:MGI:3761956
PMID:17715136[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101782
MGI:MGI:104696

P

From MGI

GO:0035725

sodium ion transmembrane transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P37091

P

From MGI

GO:0050699

WW domain binding

MGI:MGI:1336453
PMID:10212229[4]

IPI: Inferred from Physical Interaction

UniProtKB:P46935
UniProtKB:P46934

F

From MGI

GO:0050699

WW domain binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P37091

F

From MGI

GO:0050699

WW domain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51170

F

From MGI

GO:0050896

response to stimulus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0716

P

From MGI

GO:0050909

sensory perception of taste

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0919

P

From MGI

contributes_to

GO:0005272

sodium channel activity

MGI:MGI:3796353
PMID:16941024[3]

IDA: Inferred from Direct Assay

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Lee IH et al. (2007) Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2. J Biol Chem 282: 29866-73 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Ahn YJ et al. (1999) Cloning and functional expression of the mouse epithelial sodium channel. Am J Physiol 277: F121-9 PubMed GONUTS page
  3. 3.0 3.1 Wakida N et al. (2006) Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-beta1 and aldosterone. Kidney Int 70: 1432-8 PubMed GONUTS page
  4. Harvey KF et al. (1999) All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+. J Biol Chem 274: 12525-30 PubMed GONUTS page
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