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MGI:Scg5

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Scg5 ( synonyms: 7B2, Sgne-1, Sgne1 )
Protein Name(s) secretogranin V,
External Links
MGI MGI:98289

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004857

enzyme inhibitor activity

MGI:MGI:3687430
PMID:8016065[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005622

intracellular

MGI:MGI:3687403
PMID:9348280[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006886

intracellular protein transport

MGI:MGI:3687403
PMID:9348280[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007218

neuropeptide signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0527

P

From MGI

GO:0007218

neuropeptide signaling pathway

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR007945

P

From MGI

GO:0016486

peptide hormone processing

MGI:MGI:1332331
PMID:10089884[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030141

secretory granule

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR007945

C

From MGI

GO:0046883

regulation of hormone secretion

MGI:MGI:1332331
PMID:10089884[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0051082

unfolded protein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P05408

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Martens GJ et al. (1994) The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2. Proc Natl Acad Sci U S A 91: 5784-7 PubMed GONUTS page
  2. 2.0 2.1 Muller L et al. (1997) Mechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not folding. J Cell Biol 139: 625-38 PubMed GONUTS page
  3. 3.0 3.1 Westphal CH et al. (1999) The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease. Cell 96: 689-700 PubMed GONUTS page
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