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MGI:Rxrb

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rxrb ( synonyms: H-2RIIBP, Nr2b2, RCoR-1, Rub )
Protein Name(s) retinoid X receptor beta,
External Links
MGI MGI:98215

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000003
InterPro:IPR001723

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008946
InterPro:IPR000536
InterPro:IPR001628

F

From MGI

GO:0003707

steroid hormone receptor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008946
InterPro:IPR000536
InterPro:IPR000003
InterPro:IPR001723

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004879

ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P28702

F

From MGI

GO:0004886

9-cis retinoic acid receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

F

From MGI

GO:0004886

9-cis retinoic acid receptor activity

MGI:MGI:50850
PMID:1312497[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:3687657
PMID:10531331[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q8CBD1

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P28702

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008946
InterPro:IPR000536
InterPro:IPR000003
InterPro:IPR001723
InterPro:IPR001628
InterPro:IPR013088

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P28702

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:50850
PMID:1312497[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000003
InterPro:IPR001628
InterPro:IPR013088

F

From MGI

GO:0030375

thyroid hormone receptor coactivator activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

F

From MGI

GO:0030522

intracellular receptor mediated signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P28702

P

From MGI

GO:0042809

vitamin D receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

F

From MGI

GO:0042974

retinoic acid receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

F

From MGI

GO:0043401

steroid hormone mediated signaling pathway

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008946
InterPro:IPR000536

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:70257
PMID:7823919[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97857
MGI:MGI:97856

F

From MGI

GO:0044212

transcription regulatory region DNA binding

MGI:MGI:4820711
PMID:18922886[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:70257
PMID:7823919[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97587
MGI:MGI:97586

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0046966

thyroid hormone receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

F

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

F

From MGI

GO:0048384

retinoic acid receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

P

From MGI

GO:0048384

retinoic acid receptor signaling pathway

MGI:MGI:50850
PMID:1312497[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0055012

ventricular cardiac muscle cell differentiation

MGI:MGI:1101382
PMID:9428411[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:98214

P

From MGI

GO:0055012

ventricular cardiac muscle cell differentiation

MGI:MGI:1101382
PMID:9428411[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857822

P

From MGI

GO:0060038

cardiac muscle cell proliferation

MGI:MGI:1101382
PMID:9428411[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:98214

P

From MGI

GO:0071300

cellular response to retinoic acid

MGI:MGI:4820711
PMID:18922886[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:2000273

positive regulation of receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

P

From MGI

GO:2001141

regulation of RNA biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49743

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Mangelsdorf DJ et al. (1992) Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev 6: 329-44 PubMed GONUTS page
  2. Lee CH & Wei LN (1999) Characterization of receptor-interacting protein 140 in retinoid receptor activities. J Biol Chem 274: 31320-6 PubMed GONUTS page
  3. 3.0 3.1 Ben-Shushan E et al. (1995) A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol Cell Biol 15: 1034-48 PubMed GONUTS page
  4. 4.0 4.1 Islam MR et al. (2008) Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter. Am J Physiol Renal Physiol 295: F1845-54 PubMed GONUTS page
  5. 5.0 5.1 5.2 Kastner P et al. (1997) Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes. Development 124: 4749-58 PubMed GONUTS page
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