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MGI:Rtn4
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Rtn4 ( synonyms: NgA, NOGO ) | |
| Protein Name(s) | reticulon 4, | |
| External Links | ||
| MGI | MGI:1915835 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001525 |
angiogenesis |
MGI:MGI:3042512 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2661228 |
P |
From MGI |
||
| GO:0005635 |
nuclear envelope |
MGI:MGI:3687794 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0005635 |
nuclear envelope |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
C |
From MGI |
||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:2388965 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
C |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:2388965 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007413 |
axonal fasciculation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0007413 |
axonal fasciculation |
MGI:MGI:4830045 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0010977 |
negative regulation of neuron projection development |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0019987 |
negative regulation of anti-apoptosis |
MGI:MGI:3687794 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0019987 |
negative regulation of anti-apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0021801 |
cerebral cortex radial glia guided migration |
MGI:MGI:4461842 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030176 |
integral to endoplasmic reticulum membrane |
MGI:MGI:3687788 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0030176 |
integral to endoplasmic reticulum membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
C |
From MGI |
||
| GO:0030176 |
integral to endoplasmic reticulum membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030308 |
negative regulation of cell growth |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030334 |
regulation of cell migration |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030517 |
negative regulation of axon extension |
MGI:MGI:3687788 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0030517 |
negative regulation of axon extension |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0030517 |
negative regulation of axon extension |
MGI:MGI:4830045 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030517 |
negative regulation of axon extension |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
F |
From MGI |
||
| GO:0033603 |
positive regulation of dopamine secretion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0042995 |
cell projection |
MGI:MGI:3045671 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043005 |
neuron projection |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
C |
From MGI |
||
| GO:0043025 |
neuronal cell body |
MGI:MGI:3045671 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043025 |
neuronal cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
C |
From MGI |
||
| GO:0043209 |
myelin sheath |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
C |
From MGI |
||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
C |
From MGI |
||
| GO:0045665 |
negative regulation of neuron differentiation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0045687 |
positive regulation of glial cell differentiation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0048679 |
regulation of axon regeneration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0050771 |
negative regulation of axonogenesis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0051930 |
regulation of sensory perception of pain |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0051960 |
regulation of nervous system development |
MGI:MGI:4830045 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060317 |
cardiac epithelial to mesenchymal transition |
MGI:MGI:4458867 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070571 |
negative regulation of neuron projection regeneration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:0071786 |
endoplasmic reticulum tubular network organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2000172 |
regulation of branching morphogenesis of a nerve |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_114019 |
P |
From MGI |
||
| GO:2000172 |
regulation of branching morphogenesis of a nerve |
MGI:MGI:4830045 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Acevedo L et al. (2004) A new role for Nogo as a regulator of vascular remodeling. Nat Med 10: 382-8 PubMed GONUTS page
- ↑ 2.0 2.1 Tagami S et al. (2000) A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity. Oncogene 19: 5736-46 PubMed GONUTS page
- ↑ 3.0 3.1 Tozaki H et al. (2002) Expression of Nogo protein by growing axons in the developing nervous system. Brain Res Mol Brain Res 104: 111-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Petrinovic MM et al. (2010) Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development 137: 2539-50 PubMed GONUTS page
- ↑ Mathis C et al. (2010) Nogo-a regulates neural precursor migration in the embryonic mouse cortex. Cereb Cortex 20: 2380-90 PubMed GONUTS page
- ↑ 6.0 6.1 GrandPré T et al. (2000) Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. Nature 403: 439-44 PubMed GONUTS page
- ↑ 7.0 7.1 Mingorance A et al. (2004) Regulation of Nogo and Nogo receptor during the development of the entorhino-hippocampal pathway and after adult hippocampal lesions. Mol Cell Neurosci 26: 34-49 PubMed GONUTS page
- ↑ Nath AK et al. (2009) Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects. PLoS One 4: e4221 PubMed GONUTS page
