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MGI:Ros1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ros1 ( synonyms: c-ros, Ros-1 ) | |
| Protein Name(s) | Ros1 proto-oncogene, | |
| External Links | ||
| MGI | MGI:97999 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0002066 |
columnar/cuboidal epithelial cell development |
MGI:MGI:80739 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0004672 |
protein kinase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004713 |
protein tyrosine kinase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:1930880 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007283 |
spermatogenesis |
MGI:MGI:2675865 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2450566 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:80739 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008283 |
cell proliferation |
MGI:MGI:1930880 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0010629 |
negative regulation of gene expression |
MGI:MGI:2675865 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2450566 |
P |
From MGI |
||
| GO:0010966 |
regulation of phosphate transport |
MGI:MGI:2675865 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2450566 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016049 |
cell growth |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016301 |
kinase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
F |
From MGI |
||
| GO:0016310 |
phosphorylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
P |
From MGI |
||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0019903 |
protein phosphatase binding |
MGI:MGI:1930880 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0019903 |
protein phosphatase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1930880 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032006 |
regulation of TOR signaling cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070372 |
regulation of ERK1 and ERK2 cascade |
MGI:MGI:1930880 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Sonnenberg-Riethmacher E et al. (1996) The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis. Genes Dev 10: 1184-93 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Keilhack H et al. (2001) Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1. J Cell Biol 152: 325-34 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Xu Y et al. (2003) Sodium-inorganic phosphate cotransporter NaPi-IIb in the epididymis and its potential role in male fertility studied in a transgenic mouse model. Biol Reprod 69: 1135-41 PubMed GONUTS page