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MGI:Ros1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ros1 ( synonyms: c-ros, Ros-1 )
Protein Name(s) Ros1 proto-oncogene,
External Links
MGI MGI:97999

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0002066

columnar/cuboidal epithelial cell development

MGI:MGI:80739
PMID:8675006[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245

F

From MGI

GO:0004713

protein tyrosine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08922

F

From MGI

GO:0004714

transmembrane receptor protein tyrosine kinase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.7.10.1

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:1930880
PMID:11266449[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08922

P

From MGI

GO:0007283

spermatogenesis

MGI:MGI:2675865
PMID:12773415[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450566

P

From MGI

GO:0007283

spermatogenesis

MGI:MGI:80739
PMID:8675006[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008283

cell proliferation

MGI:MGI:1930880
PMID:11266449[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0010629

negative regulation of gene expression

MGI:MGI:2675865
PMID:12773415[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450566

P

From MGI

GO:0010966

regulation of phosphate transport

MGI:MGI:2675865
PMID:12773415[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450566

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016049

cell growth

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08922

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0019903

protein phosphatase binding

MGI:MGI:1930880
PMID:11266449[2]

IPI: Inferred from Physical Interaction

UniProtKB:P29350

F

From MGI

GO:0019903

protein phosphatase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08922

F

From MGI

GO:0030154

cell differentiation

MGI:MGI:1930880
PMID:11266449[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032006

regulation of TOR signaling cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08922

P

From MGI

GO:0070372

regulation of ERK1 and ERK2 cascade

MGI:MGI:1930880
PMID:11266449[2]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Sonnenberg-Riethmacher E et al. (1996) The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis. Genes Dev 10: 1184-93 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Keilhack H et al. (2001) Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1. J Cell Biol 152: 325-34 PubMed GONUTS page
  3. 3.0 3.1 3.2 Xu Y et al. (2003) Sodium-inorganic phosphate cotransporter NaPi-IIb in the epididymis and its potential role in male fertility studied in a transgenic mouse model. Biol Reprod 69: 1135-41 PubMed GONUTS page
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