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MGI:Rnf111

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rnf111 ( synonyms: Arkadia )
Protein Name(s) ring finger 111,
External Links
MGI MGI:1934919

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000209

protein polyubiquitination

MGI:MGI:3628833
PMID:16601693[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000209

protein polyubiquitination

MGI:MGI:3628833
PMID:16601693[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1096327

P

From MGI

GO:0000209

protein polyubiquitination

MGI:MGI:3628833
PMID:16601693[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0004842

ubiquitin-protein ligase activity

MGI:MGI:3628833
PMID:16601693[1]

IMP: Inferred from Mutant Phenotype

F

From MGI

GO:0004842

ubiquitin-protein ligase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6ZNA4

F

From MGI

GO:0005515

protein binding

MGI:MGI:3628833
PMID:16601693[1]

IPI: Inferred from Physical Interaction

UniprotkB:O35625

F

From MGI

GO:0005515

protein binding

MGI:MGI:4359363
PMID:17510063[2]

IPI: Inferred from Physical Interaction

UniProtKB:P12755

F

From MGI

GO:0005634

nucleus

MGI:MGI:2150845
PMID:11555636[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:3628833
PMID:16601693[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6ZNA4

C

From MGI

GO:0005730

nucleolus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6ZNA4

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3628833
PMID:16601693[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6ZNA4

C

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007389

pattern specification process

MGI:MGI:1933509
PMID:11298452[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2680166

P

From MGI

GO:0008152

metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0436

P

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001841

F

From MGI

GO:0016567

protein ubiquitination

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6ZNA4

P

From MGI

GO:0016874

ligase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0436

F

From MGI

GO:0030511

positive regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:3628833
PMID:16601693[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030511

positive regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:3628833
PMID:16601693[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030579

ubiquitin-dependent SMAD protein catabolic process

MGI:MGI:3628833
PMID:16601693[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030579

ubiquitin-dependent SMAD protein catabolic process

MGI:MGI:3628833
PMID:16601693[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0031398

positive regulation of protein ubiquitination

MGI:MGI:3628833
PMID:16601693[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031398

positive regulation of protein ubiquitination

MGI:MGI:3628833
PMID:16601693[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043234

protein complex

MGI:MGI:3628833
PMID:16601693[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:3628833
PMID:16601693[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6ZNA4

P

From MGI

GO:0046332

SMAD binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001100306

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 Liu W et al. (2006) Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia. EMBO J 25: 1646-58 PubMed GONUTS page
  2. Nagano Y et al. (2007) Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling. J Biol Chem 282: 20492-501 PubMed GONUTS page
  3. Sutherland HG et al. (2001) Large-scale identification of mammalian proteins localized to nuclear sub-compartments. Hum Mol Genet 10: 1995-2011 PubMed GONUTS page
  4. Episkopou V et al. (2001) Induction of the mammalian node requires Arkadia function in the extraembryonic lineages. Nature 410: 825-30 PubMed GONUTS page
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