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MGI:Rnasen

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Drosha ( synonyms: Etohi2, Rnasen )
Protein Name(s) drosha, ribonuclease type III,
External Links
MGI MGI:1261425

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003723

RNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From MGI

GO:0003723

RNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR014720
InterPro:IPR011907
InterPro:IPR000999

F

From MGI

GO:0003725

double-stranded RNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001159

F

From MGI

GO:0004518

nuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

F

From MGI

GO:0004519

endonuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0255

F

From MGI

GO:0004521

endoribonuclease activity

MGI:MGI:4462112
PMID:20424607[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004525

ribonuclease III activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.1.26.3

F

From MGI

GO:0004525

ribonuclease III activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011907
InterPro:IPR000999

F

From MGI

GO:0005515

protein binding

MGI:MGI:4359572
PMID:19632182[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q99MR6

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001159
InterPro:IPR014720

C

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0006396

RNA processing

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000999

P

From MGI

GO:0010586

miRNA metabolic process

MGI:MGI:4462112
PMID:20424607[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016075

rRNA catabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011907

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0031054

pre-miRNA processing

MGI:MGI:4359358
PMID:18604195[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042254

ribosome biogenesis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0690

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0255

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.1.26.3

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011907
InterPro:IPR000999

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:4462112
PMID:20424607[1]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Cheloufi S et al. (2010) A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature 465: 584-9 PubMed GONUTS page
  2. Gruber JJ et al. (2009) Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell 138: 328-39 PubMed GONUTS page
  3. Rybak A et al. (2008) A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 10: 987-93 PubMed GONUTS page
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