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MGI:Rln1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rln1 ( synonyms: rlx )
Protein Name(s) relaxin 1,
External Links
MGI MGI:97931

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005102

receptor binding

MGI:MGI:63317
PMID:8216305[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005622

intracellular

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P01347

C

From MGI

GO:0007188

G-protein signaling, coupled to cAMP nucleotide second messenger

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P01347

P

From MGI

GO:0010749

regulation of nitric oxide mediated signal transduction

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P01347

P

From MGI

GO:0010749

regulation of nitric oxide mediated signal transduction

MGI:MGI:3840054
PMID:19073841[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2668458

P

From MGI

GO:0048589

developmental growth

MGI:MGI:2668302
PMID:12861045[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2668458

P

From MGI

GO:0060736

prostate gland growth

MGI:MGI:2668302
PMID:12861045[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2668458

P

From MGI

NOT

GO:0060736

prostate gland growth

MGI:MGI:3851069
PMID:19261221[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2668458

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Büllesbach EE & Schwabe C (1993) Mouse relaxin: synthesis and biological activity of the first relaxin with an unusual crosslinking pattern. Biochem Biophys Res Commun 196: 311-9 PubMed GONUTS page
  2. Mookerjee I et al. (2009) Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2. FASEB J 23: 1219-29 PubMed GONUTS page
  3. 3.0 3.1 Samuel CS et al. (2003) Relaxin is a key mediator of prostate growth and male reproductive tract development. Lab Invest 83: 1055-67 PubMed GONUTS page
  4. Ganesan A et al. (2009) Normal prostate morphology in relaxin-mutant mice. Reprod Fertil Dev 21: 440-50 PubMed GONUTS page
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